My Ozempic is causing the most disgusting side effect and it's really getting to me... I don't know what to do'
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A weight-loss drug user revealed an unpleasant side effect of the drug that has taken a toll on her mental and physical health.

The woman, who posted on Reddit, said she was on Ozempic but did not specify how long she had used the drug or how much weight she had lost.

She wrote: ‘Since Friday, after I drank my usual protein smoothie with banana and chia seeds, I’ve been dealing with nonstop sulfur burps.

‘It’s now Monday night and still going.’

She added: ‘I’ve had short episodes like this before on Ozempic, but with diarrhea, usually lasting a couple days and then disappearing.

‘But this time it’s dragging on and it’s honestly ruined my mood. I’m worried it could be something more serious.’

Sulfur burps are burps with a strong, unpleasant odor, similar to rotten eggs, that can be caused by the buildup of gases in the digestive tract.

The FDA does list eructation, or burps, as a potential side effect of Ozempic, but says these are rare, only occurring in one percent of patients. 

Clinics, conversely, have reportedly stated that around one in five patients using GLP-1 medications—which include Wegovy, Mounjaro, and Zepbound—experience these side effects while on the medication.

Amy Schumer, 44, is shown above in an Instagram photo posted this week. She said life was not ‘livable’ while she was taking Ozempic

This is just one of numerous side effects associated with this drug, with symptoms such as nausea, vomiting, and indigestion being the most prevalent, affecting up to one in five individuals.

Specialists explain that these burps arise because the medication slows down food movement through the digestive system, resulting in longer fermentation within the stomach and the release of unpleasant-smelling gases.

For those taking Ozempic, reports caution that consuming foods high in fat can increase the likelihood of experiencing burps, as these foods will remain in the stomach for an extended period.

Dr Karen Berger, a community pharmacist, told Very Well Health that sulfur burps are generally harmless and not a sign of an underlying condition.

However, she cautioned that if burps occur frequently or are accompanied by other symptoms such as stomach pain or diarrhea, this could indicate a more serious condition, necessitating a visit to a doctor.

Currently, about one in eight Americans have tried a GLP-1 medication, and approximately 5 million US adults were using these drugs as of May 2025, according to a report from the non-profit organization Fair Health.

The post on the subredit r/Ozempic by user BBW_1409 continued: ‘What’s weird is that right after I eat, the burps seem to go away or at least get masked, but then they creep back in. 

‘A bit of bloating but no pain, or diarrhea this time — just the rotten-egg burps.’

Comedian and actor Stephen Fry, 66, says he lost an astonishing 70lbs in just four months after taking the weight loss drug Ozempic, but suffered chronic bouts of vomiting

Comedian and actor Stephen Fry, 66, says he lost an astonishing 70lbs in just four months after taking the weight loss drug Ozempic, but suffered chronic bouts of vomiting

She continued: ‘Since it started, I stopped eating except for rusks, rice with some grated cheese. Yesterday I thought it stopped and added some creamier chicken with the rice, and it restarted.’

Other users were quick to respond, also saying that they had experienced the burps after consuming fat-laden foods.

One said: ‘I used to get them constantly and then one day they just stopped; It was kind of shocking.’

A second said: ‘It was my enemy, found out that it happens only if I don’t consume [a] good amount of protein… and when I skip some meals’.

A third person said: ‘In most cases, [the burps are] just [a] reaction to excess fat amounts in your food. Cut fats to minimal amounts for a week and it will likely go away.’ 

Others said they found the burps subsided only after they cut down on red meat, onions, garlic, carbonated drinks and anything fried.

GLP-1 injections can come with more serious side effects, as well, including suicidal ideation and life-threatening intestinal blockages. 

Amy Schumer is among the celebrities to reveal she lost weight after using Ozempic and then Mounjaro, but she said she had to stop because of the side effects.

The 44-year-old took Ozempic in 2023, but said in an appearance on ‘The Howard Stern Show’ in January that she quickly had to quit the drug.

She told Stern: ‘So I tried Ozempic almost three years ago, and I was like bedridden. I was vomiting. And then you have no energy.’

Weight loss drugs have taken the US by storm, with about one in eight Americans now having tried the drugs

Weight loss drugs have taken the US by storm, with about one in eight Americans now having tried the drugs

‘I tried it and I was vomiting and I’m in bed and my son’s like, “Can you play tag?” I’m like, “I can’t.” I was shriveling.’

In a separate interview in 2023 on the Watch What Happens Live show, she said that life was not ‘livable’ for her while she was on Ozempic.

Actor and comedian Stephen Fry, 68, revealed a similar situation in March last year, saying he had also tried Ozempic for weight loss, but had to quit due to the side effects, although he did manage to lose 70lbs while on the drug.

Speaking on the River Cafe Table 4 podcast, he said: ‘I tried Ozempic years ago; I’m an early adopter of these things.  

‘I happened to be in America, and I’d read about it, and I asked my doctor in America, my physician as they like to call them, and he said, “I think I can get you some”.

‘He tried me on it, and the first week or so, I was thinking, “This is astonishing. Not only do I not want to eat, I don’t want any alcohol of any kind. This is going to be brilliant”.

‘Then I started feeling sick, and I started getting sicker and sicker and sicker. I was literally throwing up four, five times a day and I thought, “I can’t do this”. So that’s it.’

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