Kelley Mack, an accomplished actress recognized for her performances in The Walking Dead and Chicago Med, sadly passed away on August 2, 2025, at the age of 33. Her family confirmed that her death was due to a rare brain tumor known as diffuse midline glioma.

This article details her battle, the nature of the disease, and statements from loved ones.

Kelley Mack’s Diagnosis and Health Struggle

In January 2025, Mack disclosed her medical condition through Instagram, sharing that she experienced persistent back pain, leg weakness, and neuropathic itching before doctors identified a tumor on her spinal cord.

“Following the biopsy surgery on my spinal cord, I’ve lost the ability to use my right leg and most of my left leg, so I now rely on a walker and a wheelchair.” — Kelley Mack

Despite radiation treatment, the aggressive tumor progressed. Her family shared updates on CaringBridge, a platform for medical journeys.

Kelley Mack, remembered for her appearance in The Walking Dead’s ninth season, succumbed to central nervous system glioma at 33 pic.twitter.com/KDoqPz8Rn7

— Pubity (@pubity) August 6, 2025

Family Statements and Tributes

Mack’s family announced her passing on Instagram:

“It is with profound sadness that we share the news of our beloved Kelley’s passing. A vibrant, passionate light has moved on to the beyond… She will be missed by many in ways words cannot convey.” — Mack Family

Co-stars like Alanna Masterson (The Walking Dead) paid tribute:

“What an incredible human. So proud to have fought alongside her in our final episode together.”

Kelley Mack’s Legacy

Beyond her acting career, Mack also excelled as a producer, writer, and voice artist, contributing to projects like Spider-Man: Into the Spider-Verse. She was a graduate of Chapman University and resided in Los Angeles for 11 years.

Her family held a remembrance in Ohio on August 16, with a Los Angeles celebration planned later.