On a glamorous Tuesday evening in Los Angeles, Melissa McCarthy turned heads as she graced the Fashion Trust US Awards, showcasing a noticeably trimmer figure.

The celebrated actress, known for her breakout role in “Bridesmaids,” dazzled in a sleek Emilio Pucci gown. The outfit, adorned with the designer’s signature swirling patterns, accentuated her remarkable transformation.

Her choice of attire, paired with a sophisticated hairstyle that drew attention to her refined jawline, sparked conversations among onlookers and fans alike.

Amidst whispers and speculations, some fans took to social media to suggest that McCarthy’s weight loss might be attributed to medication, with one user commenting on X about a possible use of Ozempic.

Estimates suggest that the comedian has shed between 75 and 95 pounds over recent years.

Despite the chatter, McCarthy has repeatedly emphasized in interviews that her weight loss has been the result of dedicated lifestyle shifts and regular exercise.

Melissa McCarthy, 55, showed off her shrinking figure during the Fashion Trust US Awards in Los Angeles on Tuesday; (R) Pictured in 2014

She has not denied using Ozempic, but she has not confirmed it either. 

Another fan chimed in, writing, ‘If that’s the case, these are the best Ozempic weight loss results in the world.’

‘She looks gorgeous & happy… Good for her!’ someone else wrote. 

Though some continued to speculate whether she took the weight-loss jab, many others thought that the star lacked the signature ‘Ozempic face,’ noting she hasn’t developed hollowed-out cheeks often associated with the drug.

‘Think she may have done it the old-fashioned way. She doesn’t have Ozempic face and was losing weight before Ozempic got popular,’ one wrote.

‘She’s been losing weight over years. Nothing extreme. She looks great & looks even better if she did it sensibly.’

Unlike most stars, McCarthy has been open about her weight loss methods and secrets.

For exercise, she previously revealed that she does Pilates and boxing.

The Bridesmaids star stunned in a form-fitting Emilio Pucci gown featuring the designer’s iconic swirling print as she hit the red carpet at the event

The dress highlighted her dramatic weight loss transformation, while her sleek, pulled-back hair emphasized a sharper and more defined jawline

The comedian is estimated to have lost anywhere from 75lbs to 95lbs over the last several years

McCarthy has insisted in several interviews that she achieved her weight loss through lifestyle changes and exercise

The look reignited speculation about whether the actress has used any weight loss medication, with one fan noting on X that she ‘looks like she’s been on Ozempic’

Many others thought that the star lacked the signature ‘Ozempic face,’ noting she hasn’t developed hollowed-out cheeks often associated with the drug

McCarthy also insisted that she avoids extreme diets. Back in 2018, she made an appearance on Charlamagne’s the Breakfast Club radio show and explained why she is not a fan of crash diets or excessive restriction to lose weight.

‘If I can destress and do it slower and stop constantly trying to be on something, it will actually work better,’ she said at the time.

‘And then it actually worked better instead of being like, “I’m gonna not do this and do this and only drink this.”‘

She also compared extreme diets to holding her breath all day and said ’14 hours in, you go bat sh*t crazy.’

‘So I was like, “I’m just gonna mellow out, give myself a break”,’ she continued. ‘After I had kids, I was just like, “I have to be realistic. It’s not gonna go fast.” But I mean, I feel great.’

McCarthy also once shared a story about a crash diet that was successful in helping her lose weight but came with many costs.

She told People late last year that when she was filming Gilmore Girls, her doctor put her on an all-liquid diet and it caused her to lose 70 pounds in four months.

‘I’d never do that again,’ she said. ‘I felt starved and crazy half the time.’

McCarthy previously revealed she does Pilates and boxing for exercise and avoids crash diets; (L) Seen in January, (R) Seen in 2012

In 2016, she told Redbook about how she is intentional about her health journey while raising two teenage daughters; she shares Vivian, 18, and Georgette, 16, with husband Ben Falcone, 52.

‘Give me your best punch in the face, and I’ll take that punch, rather than have my kid feel bad about herself,’ she told the outlet nearly a decade ago when her kids were much younger.

‘There’s an epidemic in our country of girls and women feeling bad about themselves based on what 0.5 percent of the human race looks like. It starts very young,’ she added.

‘My message is that as long as everybody’s healthy, enjoy and embrace whatever body type you have.’