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An eighth presumptive case of monkeypox has been detected in the U.S., with Sacramento County – in Northern California – officials reporting that they had detected a ‘likely’ case of the rare virus that has rampaged across the western world in recent weeks.
County officials said that they were first notified of the case on May 21 by the unnamed person’s primary care doctor. They had returned from a trip to Europe at least one day earlier. It is unclear when the first symptoms of the virus emerged.
The person is isolating at home as officials contact trace who they may have interacted with while infectious – including others who were on the plane when they flew back into the U.S.
It comes a day after two more suspected cases were reported in the U.S., by officials in opposite corners of the nation.
Officials in Washington state said a man in King County — which includes Seattle — tested positive for the family of viruses that includes monkeypox after recently returning from abroad. He is now isolating at home and awaiting confirmatory test results from the Centers for Disease Control and Prevention (CDC).
Health chiefs warn it is a ‘possibility’ that other cases will crop up in the state, although say they have found ‘no evidence’ of onward transmission so far.
Florida also revealed a second suspected case on Monday in another individual from Broward County — which borders Miami. It was not clear whether this was linked to the first reported Sunday in the same county.
America now has six suspected cases of monkeypox, with one also in New York City and two in Utah. One case has been confirmed in Boston, Massachusetts, so far.
None of the individuals have been named, but the CDC revealed Monday that they were all male and had travelled internationally over the last month.
Globally, the total has surged to more than 170 cases confirmed in at least 20 nations — mostly in Europe — including the UK, France and Italy.
Cases are being disproportionately detected among gay and bisexual men, with experts suggesting the outbreak is linked to sex at two raves in Spain and Belgium.
Concerns have also been raised that the disease — endemic to west Africa — has evolved to become more infectious after tests revealed it had acquired an extra 50 mutations. But the World Health Organization (WHO) said yesterday that there was no sign the virus had become more transmissible.
The suspected case in California now makes the Golden State the sixth to have at least one potential case within its borders, and brings the overall tally to eight presumptive cases
The above map shows the number of cases that are confirmed and suspected across the world, including in the US. The outbreak is mostly focused in Europe at present
The disease, first discovered in lab monkeys in the late 1950s, is usually mild but can cause severe illness in some cases. It can kill up to 10 percent of people it infects. But this outbreak is of the milder, West African, strain of the virus — which has a mortality rate of around one in every 100 cases.
Monkeypox has an incubation period of anywhere up to 21 days, meaning it can take three weeks for symptoms to appear. Patients then remain infectious for as long as they have warning signs of the disease.
Symptoms include fever, headache, muscle aches, backache, swollen lymph nodes, chills and exhaustion. A rash can also develop, often beginning on the face, which then spreads to other parts of the body — including the genitals. The rash can look like chickenpox or syphilis, and scabs can form which then fall off.
Moderna testing monkeypox vaccine in the US and Europe
Moderna has revealed it is testing a potential monkeypox vaccine in the U.S. and Europe.
The major Covid vaccine manufacturer said it was taking the action amid concern at the World Health Organization over the outbreak.
Its vaccine is currently at the ‘pre-clinical level’ and it is unclear which technology it would use.
Monkeypox is normally found in west Africa where it spreads to humans from animals including squirrels.
But a recent spate of cases has seen it crop up in countries where it is not normally found.
European health chiefs warn the virus could become endemic on the continent if it manages to spread to animals there.
Dr Olivia Kaisye, a Sacramento official, said in a statement that the ‘risk to the general public is extremely low,’ for the virus at this point.
In Washington state local health chief Dr Jeff Duchin said there was currently ‘no evidence’ of further spread in the area — although he did not rule it out.
‘The risk to the public is low,’ he said, ‘but it’s important for clinicians and the public to be aware of the symptoms and risk factors for monkeypox’.
More than 200 people, mostly health care workers, are currently being monitored for monkeypox infection in Massachusetts.
But the risk that the individuals have caught the virus is low, because it typically requires sustained skin-to-skin contact.
U.S. officials were monitoring six people for a potential infection after they sat within three rows of a case on a seven-hour flight from Nigeria to the UK. There has been no subsequent report that any tested positive.
Monkeypox is generally spread through touching infectious skin lesions, but can also be passed on through droplets in the air.
At a CDC briefing yesterday Dr John Brooks, a medical epidemiologist at the agency, said in this outbreak many patients had lesions in the genital area.
He added that in some instances they are being mistaken for a ‘very bad’ case of herpes.
The CDC said yesterday that it had opened vaccination stocks to treat ‘high risk’ people exposed to the virus.
More than 1,000 doses of Jynneous — a vaccine which can treat both monkeypox and smallpox — are now being given to high-risk individuals in the United States.
People receiving the shot can get their first jab shortly after potential exposure to bolster their immunity levels. They must also get a second jab within four weeks.
The CEO of Bavarian Nordic — which makes the vaccine — revealed Tuesday they had been inundated with calls.
He told CNBC: ‘We are ramping up production as we speak and hopefully will be able to provide doses. We have already provided some doses to some European countries, and we are doing so with more this week.’
People who are infected with monkeypox often suffer from severe rashes, skin lesions and flu like symptoms. The virus kills around one-in-ten people it infects, though there is belief that the current strain making its way around the world has a mortality rate of one percent
Concerns have been raised that monkeypox has evolved ‘far more’ than expected, as the virus usually only seen in western Africa continues to sweep the world.
Portuguese virologists, tasked with conducting Covid-like studies to trace the virus’s evolution, claim the strain currently circulating is very similar to one that cropped up in Britain four years ago.
But samples taken from a handful of patients struck down in the fresh outbreak suggest the virus has collated an extra 50 mutations.
Researchers wrote that this was ‘far more than one would expect considering the estimated substitution rate for orthopoxviruses’. They also warned that an ‘evolutionary jump’ — like with the Covid Omicron strain — may have created a ‘hyper-mutated virus’.
Meanwhile, the Danish manufacturer of the smallpox vaccine, which is also effective against monkeypox, last year warned outbreaks were becoming more frequent. It claimed it could be down to the virus’s ‘genetic evolution’.
But experts are still analyzing the monkeypox genome and the WHO said yesterday there was no sign that it had mutated. The current strain circulating globally is much milder than other viruses.