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A study found that a compound in chocolate could affect the ageing process (Image: Getty)
A tasty snack might contribute to slowing the ageing process. Studies suggest that a particular compound present in chocolate could potentially help maintain a more youthful state.
Indulging in your favorite chocolate treat might do more than satisfy your sweet tooth—it could also slow down the aging process, according to recent research. A specific compound found in chocolate is showing promise in helping maintain youthfulness.
Scientists at King’s College London have pinpointed theobromine, a naturally occurring compound in cocoa, as a potential anti-aging agent. Their study, published in the journal “Ageing,” examined the levels of theobromine in participants’ blood and its association with biological aging markers.
Unlike chronological age, which simply counts the years since birth, biological age reflects how well the body functions and its overall health. This is measured through specific DNA markers known as methylation, which naturally change over time.
The study analyzed data from two European groups: 509 participants from TwinsUK and 1,160 from KORA. Findings indicated that individuals with higher levels of theobromine in their bloodstream tended to have a biological age that was younger than their actual age.
Professor Jordana Bell, a leading author of the study and an expert in Epigenomics at King’s College London, stated, “Our research highlights a connection between a key component of dark chocolate and prolonged youthfulness.”
People with elevated theobromine levels in their bloodstream had a younger biological age (Image: Getty)
Nevertheless, she warned that these results shouldn’t be interpreted as permission to consume excessive amounts of chocolate. According to a King’s College London release, she commented: “While we’re not saying that people should eat more dark chocolate, this research can help us understand how everyday foods may hold clues to healthier, longer lives.”
The research team also examined whether additional compounds found in cocoa and coffee showed comparable correlations.
However, she cautioned against overindulging in chocolate. In a statement from King’s College London, Bell noted, “We’re not suggesting people should increase their dark chocolate intake. This study is more about understanding how everyday foods might offer insights into living healthier, longer lives.”
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One analysed chemical alterations in DNA to determine the rate at which an individual is ageing.
The second method evaluated telomere length, the protective caps located at the ends of chromosomes. Reduced telomere length is associated with the ageing process and conditions related to advancing years.
Dietary plant compounds may affect how our bodies age by modifying the way our genes are switched on or off. Certain of these substances, called alkaloids, can engage with the cellular systems that govern gene activity and contribute to determining wellbeing and lifespan.
Theobromine, an alkaloid most notably known for its toxicity to canines, has been connected with health benefits in people, including decreased cardiovascular disease risk. However, it has not received extensive research attention beyond this.
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Dr Ramy Saad, lead researcher at King’s College London, who is additionally affiliated with University College London and practises as a clinical genetics physician, remarked: “This is a very exciting finding, and the next important questions are what is behind this association and how can we explore the interactions between dietary metabolites and our epigenome further? This approach could lead us to important discoveries towards ageing, and beyond, in common and rare diseases.”
The scientific team, featuring Professor Ana Rodriguez-Mateos, Professor of Human Nutrition at King’s College London, is exploring potential avenues for further investigation to scrutinise these results more comprehensively. A key outstanding question is whether this phenomenon is attributable solely to theobromine, or whether theobromine might operate in conjunction with other components present in dark chocolate, including polyphenols, which are acknowledged for their beneficial effects on human well-being.
Dr Ricardo Costeira, postdoctoral research associate at King’s College London, observed: “This study identifies another molecular mechanism through which naturally occurring compounds in cocoa may support health. While more research is needed, the findings from this study highlight the value of population-level analyses in ageing and genetics.”
Nevertheless, despite these promising findings, the researchers stress that merely increasing dark chocolate consumption isn’t automatically beneficial, given that it also contains sugar, fat and other substances, and further investigation is needed to understand this connection more thoroughly.