I lost four stone on Mounjaro... but it was this surprising side-effect it had on my ADHD that completely changed my life
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When Georgie Robinson began weekly injections of Mounjaro, she hoped it would help her shed the excess weight she had carried for more than a decade.

What she hadn’t anticipated was the remarkable impact that the popular weight loss injection would have on her ADHD, a condition she had grappled with for as long as she could recall.

Attention deficit hyperactivity disorder interferes with focus, impulse management, and the ability to stay orderly. For 33-year-old Georgie, it resulted in perpetual restlessness, incomplete duties, and the sensation, as she described it, of being ‘bad at life’.

She states: ‘I had hoped the injection would assist in losing weight. However, I noticed that when I took them, it was like the noise in my mind quieted down. I could organize laundry, operate the dishwasher, tidy up the house – activities that had previously felt unattainable.’

Georgie, from Petersfield in Hampshire, lives with her sales director husband Greg and their six-year-old daughter Margo.

Initially an enthusiastic hockey player, she eventually gained weight until she hit her peak at 21st. ‘I worked out with a personal trainer two or three times weekly, I maintained a healthy diet, but the weight simply wouldn’t budge,’ she explains.

Georgie Robinson was struggling with her weight and ADHD when she started taking Mounjaro weight-loss jabs

Georgie Robinson was struggling with her weight and ADHD when she started taking Mounjaro weight-loss jabs

After several months of indecision, she opted to try Mounjaro. Within ten weeks on the smallest 2.5mg dose, she shed two stone. In the ensuing months, her weight loss decelerated, but she ultimately lost a total of 4st. She resumed playing hockey.

Simultaneously, Georgie was exploring another theory: ADHD. Awareness and diagnoses have surged recently, especially among women, as medical professionals acknowledge that the condition – afflicting approximately 2.6 million people in the UK – often appears differently from the hyperactive boys it was previously believed to primarily affect.

Recalling her diagnosis in March, after a video consultation, Georgie says: ‘I felt like a weight had lifted off me. For the first time in years, I could stop blaming myself.’

The revelation of just how much Mounjaro was helping came by accident. Last month, when a price hike left her without the drug for two weeks, she says the cravings for high calorie treats returned – but so did her ADHD symptoms.

Georgie says: ‘I felt hungrier, I expected that, but what shocked me was my brain. Suddenly I couldn’t finish jobs. I was back to half-done tasks, impulsive spending, emotional ups and downs.

‘When I restarted Mounjaro, it all settled again. I could focus, I could tick off my to-do lists.’

Georgie was 21st at her heaviest weight

Within ten weeks on the lowest 2.5mg dose of Mounjaro, she had lost 2st

Within ten weeks on the lowest 2.5mg dose of Mounjaro, Georgie had lost 2st 

Doctors have long known that blood-sugar fluctuations can affect mood, concentration and impulsivity. Mounjaro, known generically as tirzepatide, was originally developed for type 2 diabetes and helps regulate insulin and appetite.

Georgie says: ‘It could just be that by changing my diet with Mounjaro, it’s stabilising my blood-sugar levels, which could be quietening my brain – but it feels like more than that.’

There is mounting evidence weight-loss jabs may have benefits far beyond slimming and diabetes control. Large clinical trials show they can slash the risk of heart disease while early studies suggest they may dampen addictive behaviours, such as alcohol cravings.

When it comes to ADHD, however, doctors stress there is no clinical trial evidence the drugs make a difference. However, anecdotal reports are emerging in patient forums – and other reports have claimed anti-diabetic medication semaglutide ‘may be able to soften the traits of ADHD’.

Another striking change for Georgie has been relief from PMDD (premenstrual dysphoric disorder), a severe form of PMS. She says: ‘Since being on Mounjaro, I haven’t had PMDD symptoms. It’s like a double gift.’

Experts caution against reading too much into such personal accounts, however. Katya Rubia, professor of cognitive neuroscience at King’s College London, says there is ‘substantial evidence of overlap’ between ADHD and obesity, which may explain why some report crossover benefits.

She adds: ‘ADHD is significantly more common among people with obesity. This relationship is complex and likely multifactorial. Shared behavioural characteristics.

‘At the biological level, there appears to be both a genetic and neurobiological overlap. Neuroimaging studies suggest shared dysfunctions in brain networks, particularly dopamine-related reward pathways and the frontal lobes.

‘This may explain why individuals with ADHD often experience food cravings. There is also evidence inflammation in the brain, potentially influenced by poor diet, may contribute to both ADHD and obesity, and this may also help explain links with depression and anxiety.

‘However, it remains difficult to determine the direction of causality – whether ADHD predisposes to obesity, obesity contributes to ADHD symptoms, or whether both share common underlying mechanisms. The relationship is likely to vary between individuals.’

But Georgie says: ‘Mounjaro gave me back my body – but the real gift is that it helped me find my mind.’

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