A pharmacist has highlighted that millions of individuals on long-term medications might be compromising their effectiveness simply by taking them at the wrong times of the day. Peter Thnoia, a superintendent pharmacist at the NHS-approved online pharmacy PillTime, states that while managing multiple prescriptions can be overwhelming, the timing of each dose is just as important as remembering to take them.

He has cautioned that failing to read instructions thoroughly can render medicines less potent and heighten the risk of adverse side effects.

“Often, individuals overlook or don’t completely adhere to the instructions that accompany their medication, which can significantly affect how well these medicines perform,” said Peter, who possesses over 20 years of experience in the pharmacy field.

“Something as simple as consuming a pill at an incorrect time of day, or not with food when required, can lessen its effectiveness or even lead to adverse side effects. Establishing a consistent schedule and understanding both the ‘when’ and the ‘what’ of your medication is crucial for achieving the optimal results for your health.”

Statins – a widespread illustration

One of the most common medications taken at unsuitable times are certain statins, which are cholesterol-lowering drugs vital for preventing heart disease. Numerous Britons, particularly those over the age of 40, are prescribed statins like simvastatin and lovastatin.

These specific statins show the greatest efficacy when consumed in the evening because the body’s cholesterol production is highest during the night. However, many people take them in the morning by habit, along with their other drugs.

“Many people take their statins in the morning, simply because it’s when they take the rest of their medication,” Peter explained.

“Particularly with types like simvastatin, research indicates they are most effective when taken in the evening – a time when the body naturally generates more cholesterol. Taking them at an inappropriate time may unknowingly diminish their effectiveness,” he explained.

Supplements and additional medicines

It isn’t solely prescribed drugs that can be influenced by timing – nutritional supplements are frequently consumed at inappropriate times, diminishing their advantages. Iron tablets, for instance, are commonly consumed during morning hours alongside breakfast or a swift cup of tea before dashing out of the house.

However, food – especially dairy products – and beverages such as tea or coffee can substantially decrease the amount of iron the body takes in.

“There are plenty of people who take morning supplements like iron tablets to ‘get them through the day’ – often gulped down quickly before heading to work,” Peter said.

“But iron is actually absorbed best on an empty stomach, and things like dairy, tea or coffee can block absorption. That’s why the best advice is to take iron tablets as soon as you get up, before breakfast.”

The significance of preparation

Peter’s advice emphasises the significance of planning – especially for individuals juggling multiple prescriptions. Leighton Humphreys, CEO of PillTime, suggests that the company’s pouching service can be a crucial aid, eliminating the stress and uncertainty of managing medicines: “I know it’s not the most exciting task, especially if you have multiple medications that need to be taken at different times of the day or night. But the only way to get the most from your medication is to carefully follow the instructions from your pharmacist.

If you can’t do that, whether due to lack of time or physical ability, there are options to have your medications pre-sorted into pouches. This means the pharmacist will review the instructions for each prescription and organise your medicines into clearly labelled pouches showing the dose, date and time. There’s no guesswork – just the right medication at the right time.”

Common medications people often take at incorrect times

Statins, like Simvastatin

Best consumed in the evening as cholesterol production peaks at night. A dose before bed can enhance effectiveness.

Iron supplements

Best on an empty stomach, ideally first thing in the morning before breakfast. Bear in mind, dairy, tea, and coffee can hinder absorption.

Levothyroxine, for an underactive thyroid

Best to take first thing in the morning, at least 30 minutes prior to consuming food and drink to minimise absorption.

Some pain relief, such as Ibuprofen and Naproxen

Known as NSAIDS, these tablets can upset the stomach – so it’s recommended to take them with food or a glass of milk.

Certain ADHD medications, such as methylphenidate

Stimulant ADHD medications can lead to insomnia if taken too late in the day, hence morning doses are advised to manage symptoms during waking hours without disturbing sleep.