() A newly unsealed superseding indictment on Wednesday exposes connections between the Sinaloa cartel in Mexico and the trafficking of fentanyl and other illegal drugs in the Midwest, as stated by federal prosecutors.

Among the 26 defendants facing drug-conspiracy charges are high-ranking members of the Sinaloa cartel who are accused of orchestrating the shipment of hundreds of kilograms of fentanyl, methamphetamine, and cocaine through Southern Illinois and the St. Louis area. The U.S. Department of Justice reported that the laundered profits were then funneled back to Mexico.

“The exceptional work of the St. Louis Field Division and their partners has led to the seizure of over 800 pounds of fentanyl and uncovered a money laundering operation that channeled millions in cartel earnings through U.S. banks,” Drug Enforcement Administrator Terrance Cole stated in a news release. “This isn’t a street-corner operation—it is a cartel pipeline that has inundated the Midwest.”

Prosecutors state that the DEA and its partners apprehended 15 defendants in a nationwide sweep. According to court documents, the drug-trafficking conspiracy mentioned in the indictment spanned from January 2020 to July 2025.

Two defendants, Mexican nationals, are also charged with narcoterrorism. It wasn’t immediately clear which defendants were in custody.

The announcement on Wednesday about the Illinois-Mexico drug nexus comes amidst the Trump administration’s designation of the Sinaloa cartel as a terrorist organization.