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A trainee solicitor tragically died from a rare blood clot weeks after taking the AstraZeneca Covid vaccine, an inquest heard today.

Oli Akram Hoque, 26, from Ilford, received a dose of the vaccine on March 19 last year before suffering increasingly ‘excruciating’ headaches.

His condition deteriorated and resulted in his death at Queen’s Hospital in Romford, on April 15, 2021 – one month before his 27th birthday.

In his written statement to East London Coroners’ Court, Oli’s grieving dad Bablul Hoque described his son as ‘bright, intelligent, and ambitious’, recalling his impressive CV which included work at Arsenal FC and the Citizens Advice Bureau. 

Mr Hoque said the City University graduate had taken the vaccine in Ilford, where he lived with both parents and ‘subsequently complained of headaches’.

Britain’s medical regulator recommended under-30s should get an alternative to the AstraZeneca vaccine in early April when it became clear that younger people were at greater risk of the clots. 

Trainee solicitor Oli Akram Hoque, 26, received a dose of the vaccine on March 19, 2021 before suffering increasingly "excruciating" headaches

Trainee solicitor Oli Akram Hoque, 26, received a dose of the vaccine on March 19, 2021 before suffering increasingly "excruciating" headaches

Trainee solicitor Oli Akram Hoque, 26, received a dose of the vaccine on March 19, 2021 before suffering increasingly “excruciating” headaches

The rare blood clot sadly resulted in Mr Hoque's death at Queen's Hospital in Romford on April 15, 2021 - one month before his 27th birthday

The rare blood clot sadly resulted in Mr Hoque's death at Queen's Hospital in Romford on April 15, 2021 - one month before his 27th birthday

The rare blood clot sadly resulted in Mr Hoque’s death at Queen’s Hospital in Romford on April 15, 2021 – one month before his 27th birthday

A total of 79 Britons have died with blood clots thought to have been caused by the AstraZeneca vaccine after being vaccinated with it — out of around 50million doses.

The vaccine can set off a chain reaction which leads to the body confusing its own blood platelets for fragments of virus.  

For reasons the scientists are still probing, the body then mistakes these platelets as a threat and produces antibodies to fight them.

The combination of the platelets and the antibodies clumping together leads to the formation of dangerous blood clots. 

Mr Hoque said Oli had gone to the Royal London Hospital ten days before his death on April 5 but was ‘discharged without proper diagnosis or investigation’ with an injection to stop him being sick. 

He said Oli ‘requested a scan to be carried out but his request was declined’. 

Later Oli had a seizure and was taken to Queen’s Hospital where a CT scan identified a blood clot, he was then put on blood thinners. He later died in hospital.

Oli’s only medical history was a childhood asthma diagnosis with no mention of migraines

Mr Hoque said: ‘I was devastated by the news. I am unable to come to terms with the fact my son Oli is no longer with us. He was only 26-years-old and had his whole life ahead of him.

What is the risk of getting blood clot after AstraZeneca’s jab? 

British health chiefs recommended all under-40s are offered an alternative to AstraZeneca’s vaccine because of blood clot fears.

UK regulators have spotted around 400 cases of the clots, including 73 deaths — out of almost 48million AZ jabs dished out.

The MHRA insists the overall benefits of the use of the AZ vaccine in the UK programme ‘outweighs the extremely rare adverse events reported to date’.

But the body still states that healthy under-40s should be ‘preferentially offered an alternative’, such as Pfizer or Moderna.

Younger people — even adults in their 30s — are known to face much smaller odds of falling seriously ill with SARS-CoV-2.

The first clots to spark alarm were ones appearing in veins near the brains of younger adults in a condition called CSVT (cerebral sinus venous thrombosis).

Since that, however, people have developed clots in other parts of their bodies and they are usually linked to low numbers of platelets, which is unusual because platelets are usually used by the immune system to build the clots.

In most cases people recover fully and the blockages are generally easy to treat if spotted early, but they can trigger strokes or heart or lung problems if unnoticed.

Symptoms depend entirely on where the clot is, with brain blockages causing excruitiating headaches. Clots in major arteries in the abdomen can cause persistent stomach pain, and ones in the leg can cause swelling of the limbs.

Researchers in Germany believe the problem lies in the adenovirus vector — a common cold virus used so both vaccines can enter the body.

Academics investigating the issue say the complication is ‘completely absent’ in mRNA vaccines like Pfizer’s and Moderna’s because they have a different delivery mechanism.

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‘He is dearly missed by everyone. I hope all the underlying factors will be taken into consideration. I sincerely hope every possible measure will be taken by the authorities to make sure this does not happen to anybody else in the future.’

Coroner Nadia Persaud then called Oli’s sister Anika Hoque to give evidence. 

Recalling the period just after the vaccination, she said: ‘He did say he had some headaches but it was not anything excruciating, it was just a headache that would go away with time. But as the time went on the pain was getting worse and worse it seems.’

By April 5 Ms Hoque recalled Oli ‘spent most of his time in bed’. She continued: ‘I said to him a couple of times he was not himself, very quiet, the headache did not seem to be going away with medicine and painkillers. 

‘Then at night I said you should go to A&E. He actually agreed too. I was quite surprised so I knew it must be serious.

‘I accompanied Oli to the Royal London Hospital on April 5. We arrived at the hospital and despite the excruciating headache Oli was suffering from we waited 20-30 minutes before a nurse came in and sent Oli to a different department. He was very slow.

‘Incredibly, we were kept waiting for what felt like the worst few hours of my life, we kept seeing patients who were seen and immediately discharged.’

She said they were eventually seen and Oli explained he had been suffering ‘severe and consistent headaches’. She added: ‘Oli mentioned he had vomited blood and feels dizzy when he stands up and had never suffered headaches like this before.’ 

During the conversation she said the doctor asked if he had taken the vaccine and he confirmed he had taken the Astra-Zeneca vaccine ‘very recently’.

Speaking to a court which included 13 lawyers acting on behalf of various health bodies, Ms Hoque said: ‘I suggested the doctor carry out a head scan but he insisted this would not be necessary and gave him some co-codamol.’

Ms Hoque explained she had looked up NHS advice on headaches and was worried about her brother due to the ‘sudden onset’ of the headaches which she understood to be a ‘red flag’. 

‘I trusted the doctor to know best, I trusted him in that moment,’ she said. 

Describing the doctor’s tone as ‘condescending’, she added: ‘At the very least he seemed to be in a rush to discharge us.’

She said: ‘It brings tears and I get overwhelmed with emotions when I remember we were on our way to leave the hospital and Oli stopped and looked very confused, he did not want to leave without a proper diagnosis.’

She told the court they then went back into the doctors room and Oli was offered an injection for his sickness. 

‘The doctor said everything is fine and gave him the injection, he said it takes about 15 minutes to kick in then he should be fine,’ she said.

Ms Hoque then recalled leaving the hospital after she said they were left on their own. However, a representative of the hospital told the court that they were told to wait. 

‘There was no reason for us to leave,’ Ms Hoque said. ‘I believe any suggestion Oli left is an oversight and attempt to mislead the coroner’s hearing.’

Closing her statement, she said: ‘The condition could have been diagnosed if it was given due attention. Young people of his age deserve better. I will not get my brother back. My parents have not recovered from the shock.’

The inquest continues.

The British-made AstraZeneca vaccine is thought to have saved about a million lives from Covid and was the backbone of the UK’s initial rollout in early 2021, helping it to become the most vaccinated country in the West.

But concerns about clots saw its restriction in under-40s in the UK in spring and led Pfizer and Moderna’s vaccines being favoured for young adults and as boosters. 

It was outright banned in many European countries and the US decided not to purchase a single dose.

The first inquest into a death linked to the AstraZeneca jab was concluded in September last year.

Mother-of-two Alpa Tailor, 35, from London, suffered a stroke a week after getting the jab with symptoms including slurred speech and a facial droop. She died two weeks later. 

In another case mother-of-two Michelle Barlow, from Wigan, died from blood clots 16 days after getting her first dose of the vaccine. Doctors initially mis-diagnosed her symptoms as gastroenteritis. 

Source: Daily Mail

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