A recent study has highlighted a concerning trend for those relying on weight loss medications: the return of lost weight and adverse health conditions within a mere two years. Published in the BMJ, the research reveals that individuals not only regain the shed kilos but also experience a resurgence of high cholesterol and blood pressure.
The study indicates that once treatment ends, weight begins creeping back at an average rate of 0.4 kilograms per month. Alongside this, health risks such as diabetes and heart disease markers are expected to revert to their initial levels in less than two years.
Interestingly, the analysis points out that weight regain after discontinuing such medications occurs almost four times faster than it does following lifestyle changes like diet and exercise. This rate holds true irrespective of the total weight lost during treatment.
The researchers noted, “This evidence suggests that, despite the initial success in achieving weight loss, these medications may not provide a sustainable solution for long-term weight management on their own.”
Although these drugs have become popular and significantly impacted obesity treatment, it is estimated that around 50% of users discontinue GLP-1 medications within just one year. This trend underscores the challenges in maintaining weight loss through pharmacological methods alone.
While the drugs are wildly popular and have transformed the treatment of obesity, it’s estimated that around half of people with obesity discontinue GLP-1 drugs within 12 months.
“The study findings cast doubt on the notion that GLP-1 receptor agonists are a perfect cure for obesity,” a US researcher said in a linked editorial.
“People taking GLP-1 receptor agonists should be aware of the high discontinuation rate and the consequences of cessation of medications.”
He said “healthy dietary and lifestyle practises” should remain the foundation of weight loss treatment and management, with the GLP-1 medications used as an aide.
“Such practises not only help prevent excess weight gain but can also lead to numerous health benefits that go beyond weight control,” he said.
