Police are trying to piece together what led to the alleged murder of a woman at her home in Perth’s north.

Officers were called to the Lansdale home around 8.30pm on Monday after neighbours reportedly heard screams coming from the property.

A 51-year-old woman was found dead at the home.

Woman found dead in Lansdale home in Perth's north
The woman was found dead inside the Lansdale home. (9News)

A man in his 50s was taken out of the house in a wheelchair and taken to hospital for treatment of his injuries.

He remains in hospital under police guard.

Family members arrived at the home a short time later and were seen consoling each other on the street.

Woman found dead in Lansdale home in Perth's north
Homicide detectives remain at the scene. (9News)

Neighbours have been left shocked by the incident.

“I know there are a lot of people that come and go from there,” one told 9News.

“There were about 40 of us standing around going, ‘Are we safe?’

“That was the worst of it I think.”

Another neighbour said: “Plenty of other nice people in the street so it’s not too concerning but just strange two doors up.”

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