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CPD said the man was in the 0-block of North Wabash Avenue about 2:50 a.m. when a male suspect approached him, poured a flammable liquid on him and set him on fire.
The suspect then went west on foot.
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A security officer from a nearby building used a fire extinguisher to put the fire out.
The man suffered burns to nearly half his body and was taken to Northwestern Memorial Hospital, where he is listed in critical condition.
No one was in custody later Wednesday morning, and Area Three detectives are investigating.
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