Brian Walshe, a 50-year-old resident of Massachusetts, is back in court for the second day of his trial, facing charges of murdering his wife after allegedly discovering her affair with a friend in Washington, D.C.

During Monday’s opening statements, Walshe’s defense attorney, Larry Tipton, argued that Walshe came across his wife’s lifeless body in bed but did not commit the crime. Tipton claimed that the evidence would point to a “sudden, unexplained death,” emphasizing that such occurrences are possible. He also refuted the prosecution’s assertion that Brian Walshe was aware of Ana Walshe’s alleged affair.

Prosecutors allege that Walshe killed Ana, dismembered her, and concealed her remains after conducting online searches related to the man she was allegedly seeing.

On December 1, 2025, Brian Walshe appeared at the Norfolk Superior Court in Dedham, Massachusetts, as he faces these serious charges regarding his wife Ana’s death. (Photo by David McGlynn for Fox News Digital)

Randolph Rice, a Maryland attorney and legal analyst observing the trial, commented, “The defense might assert that the search reveals awareness of a name, not necessarily knowledge of a romantic entanglement. This distinction is crucial, as lacking definitive knowledge of an affair weakens the state’s argument regarding motive.”

Brian Walshe has already admitted to lesser charges of misleading authorities and the unlawful disposal of human remains.

Cohasset Police Sgt. Harrison Schmidt will come back to the stand after prosecutors said they intend to continue questioning him and also to play about 40 minutes of additional excerpts from his interviews with Walshe prior to the defendant’s arrest. 

Prosecutors played more than an hour of similar recordings Monday, in which Walshe spoke calmly with detectives with sporadic interruptions from his three children as their mother was unaccounted for in early January 2023.

“I would never do anything to my wife,” he told Schmidt at one point, after Ana’s death. “I wanted to spend the rest of my life with my wife. I’m still going to.”

Brian and Ana Walshe raise a toast on their wedding day in the lounge of L’Espalier in Boston, Massachusetts, on Monday, Dec. 21, 2015. (Obtained by Fox News Digital)

Massachusetts State Trooper Nicholas Guarino, an expert on digital forensics, is expected to take the stand next and discuss Walshe’s alleged Google searches, which included the name of the man involved in an affair with Ana, 39, and for information on how to dispose of human remains.

Guarino testified earlier this year in another high-profile Massachusetts murder trial, reading text messages sent between Karen Read and John O’Keefe. Read was acquitted of all homicide-related charges in the death of her former boyfriend, O’Keefe, and convicted of drunken driving. 

Ana Walshe pictured in a November 2022 Instagram post. (Ana Walshe/Instagram)

Prosecutors have alleged two possible motives in the case. 

The first is that Walshe allegedly uncovered an affair between his wife and a Washington, D.C., realtor, who is expected to take the witness stand Thursday. 

William Fastow leaves an open house in the Spring Valley area of Washington, D.C., Saturday, Nov. 29, 2025. Fastow was a friend of the late realtor, Ana Walshe, and is suspected of being involved in an affair with her before her death. (Fox News Digital)

The other is that Walshe allegedly believed that if his wife was out of the picture, and he was the only caretaker for their three children, he could have a chance of avoiding prison in connection with a federal art fraud conviction.

He faces up to life in prison without parole if convicted in Ana’s death. Her remains have not been found.