University of Washington School of Medicine body clock tool calculates people's biological age
Share this @internewscast.com

Researchers have developed a new “body clock” tool that calculates people’s biological age — and could even predict the risk of disability or death.

The University of Washington (UW) School of Medicine has developed a tool that evaluates a patient’s health by using eight distinct metrics from physical examinations and blood tests, as detailed in a UW press release.

The tool’s method — officially named the Health Octo Tool — is detailed in the journal Nature Communication in a May 5 publication.

Dr. Shabnam Salimi, the study’s lead author and a physician-scientist as well as an acting instructor in UW’s Department of Anesthesiology & Pain Medicine, suggests that this approach offers a more holistic view compared to current health assessments, which generally concentrate on specific diseases rather than assessing complete well-being.

By analyzing data from extensive longevity studies, the Health Octo Tool demonstrated an ability to predict aspects such as disability, geriatric syndrome (which encompasses various prevalent health issues among older individuals), the Short Physical Performance Battery (a clinical measure of lower body functioning in seniors), and mortality with an accuracy rate of 90% or higher, according to the study findings.

“An aging-based framework offers a new path to discover biomarkers and therapeutics that target organ-specific or whole-body aging, rather than individual diseases,” Salimi said in the release.

The tool focuses on “health entropy,” which encompasses the amount of molecular and cellular damage the body has sustained over time.

That has a direct impact on the function of a person’s organs and overall body systems, which can be used to determine how fast they are aging, the researchers noted.

The tool starts by assigning a “body organ disease number,” ranging from 1 to 14, based on whether the patient has experienced any diseases affecting the heart, lungs, brain or other specific organ systems.

“Our findings demonstrated that organ systems age at different rates, prompting us to develop a Bodily System-Specific Age metric to reflect the aging rate of each organ system and the Bodily-Specific Clock to represent each organ system’s intrinsic biological age,” Salimi said. 

“Extending this concept to the whole body, we define the Body Clock as a composite measure of overall intrinsic age and body age as the corresponding rate of aging.”

Two of the components of the tool, Speed-Body Clock and Speed-Body Age, measure how biological age affects walking speed.

The Disability-Body Clock and Disability-Body Age components measure aging’s impact on cognitive function and physical disability, the release stated.

One takeaway from the research was that some seemingly minor conditions, such as untreated hypertension early in life, could have a significant impact on aging in later years, according to Salimi.

This indicates that treating these conditions sooner could slow down biological aging.

Looking ahead, the researchers plan to develop a digital app that people can use to track their own biological age, track how fast they are aging, and measure the impact of lifestyle changes.

“Whether someone is adopting a new diet, exercise routine or taking longevity-targeting drugs, they will be able to visualize how their body — and each organ system — is responding,” said Salimi.

Dr. Brett Osborn, a Florida neurosurgeon who also runs a longevity practice, was not involved in the tool’s development, but commented on its potential benefits and limitations.

“This tool distinguishes itself by basing its model on readily accessible physical exam findings and standard lab tests, offering a potentially practical framework for clinical application,” he told Fox News Digital. 

“An app is also being developed to empower patients and potentially encourage the development of health habits that will positively impact their healthspan — or how long they will remain functional and disease-free.”

The doctor also praised the Octo Tool’s focus on system-based aging metrics rather than disease-specific assessments.

Osborn noted, however, that there are limitations to these types of proposed biological aging clocks — primarily that they can’t counter the “inherent complexity of aging.”

“Aging is not a linear or wholly quantifiable process — it is influenced by myriad known and unknown genetic, molecular, environmental and psychosocial factors,” the doctor said.

“It is a truly ‘analog’ and ‘non–digital’ process. Therefore, it should be no surprise that no model has captured its entire landscape.”

UW’s tool doesn’t take into account certain genetic and DNA processes that influence biological aging, Osborn noted.

“Aging clocks have also often fallen short when applied across diverse populations or when predicting individual outcomes (lifespan),” he added.

Rather than determining absolute biological age, Osborn suggests using these tools to track trends over time.

“For example, tools like the Health Octo can help evaluate an individual’s response to interventions — be it a new exercise regimen, medication or lifestyle change.” 

The most important thing, according to Osborn, is to use comprehensive testing and tracking as a springboard to the formation of lifelong health habits. 

“If it saves one person’s life by bringing their ailing health (manifested as a downward trend) to their attention, that’s a win,” he said.

The research was supported by a National Institutes of Health grant from the U.S. National Institute on Aging.

Share this @internewscast.com
You May Also Like
'I couldn't stay silent anymore'

‘I Had to Speak Up’

Actor Derek Dixon from “The Oval” has stepped forward after filing a…
South River, New Jersey police officers save 1-year-old choking child, body camera video shows

Heroic South River Police Officers Rescue Choking Toddler in Heart-Pounding Bodycam Footage

SOUTH RIVER, N.J. — Police officers in New Jersey jumped into action…
Sheriff Cook discusses safety and crime at town hall

Sheriff Cook Talks Crime and Safety Issues at Community Town Hall

During Thursday’s town hall, Sheriff Michelle Cook announced that crime in Clay…
State Department firing more than 1,300 employees under President Donald Trump administration plan, officials say

Trump Administration’s Plan Leads to Over 1,300 State Department Employee Dismissals, Officials Report

The State Department is set to terminate over 1,300 employees this Friday…
Mugshot of a man in a yellow shirt.

Justin Mohn Convicted of Murdering Father and Posting Disturbing Video Online

A SICK man who slashed his dad’s head with a machete and…
Photo of Carolina Wilga at a petrol station.

Backpacker Carolina Winger, 26, Found Alive After Nearly Two Weeks Lost in Australian Wilderness

A GERMAN backpacker missing for nearly two weeks in the remote Australian…
Helicopter dropping cash from the sky.

Witness the chaos as deceased man’s fortune is released by helicopter, igniting a frantic dash as onlookers snatch bundles of money.

THIS is the moment a dead man’s life savings are dropped from…
El Chapo's son pleads guilty to US drug trafficking

El Chapo’s Son Admits Guilt in US Drug Trafficking Case

As part of a plea agreement, Guzman Lopez admitted to helping oversee…
Admiral Kuznetsov aircraft carrier in the English Channel.

Russia’s Sole Ailing Aircraft Carrier, Once Struggling Through the Channel, Set to Be Retired

VLADIMIR Putin’s only rustbucket aircraft carrier that struggled through the Channel is…
Trump calls Butler widow, Secret Service agrees to meeting after call for accountability

Trump Phones Widow of Butler: Secret Service Accepts Meeting Following Demand for Responsibility

The widow of Corey Comperatore, a victim of a shooting at a…
Carsten and Vivian Spohr at the Cannes Film Festival.

Wife of Airline CEO Allegedly Hits and Kills Babysitter, 24, With Car Before Leaving Vacation Island

THE wife of a billionaire airline CEO ran down and killed a…
Georgia teen who raised 'awareness' about mother, stepfather's deaths on TikTok now charged with their murder

Georgia Teen Who Publicly Mourned Parents on TikTok Is Now Charged with Their Murders

In Georgia, a teenage girl is facing charges for the alleged murders…