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Captain Maguire has a knee issue and winger Sancho is suffering from tonsillitis, with Paul Pogba, Fred, Edinson Cavani and Luke Shaw also ruled out.
United’s interim manager Ralf Rangnick has already written off his team’s chances of finishing in the top four and qualifying for next season’s Champions League.
Manchester United captain Harry Maguire has suffered a knee injury and will miss Thursday night’s match against Chelsea at Old Trafford
But their hopes of finishing a thoroughly underwhelming season on something of a high in the final four games will be diminished by a number of key absentees.
Rangnick said: ‘Fred is not yet available. He trained yesterday but I had a chat with him and he said he’s not fully fit.
‘It doesn’t make sense to play him too early, so he won’t be available.
‘Harry Maguire – it’s not a big thing but he didn’t train yesterday. Paul, obviously, Fred, Edinson, Luke Shaw and Jadon. He has tonsillitis and couldn’t train yesterday.
‘We will try to play the best possible team of the players available.’
With matches against Chelsea, Brentford, Brighton and Crystal Palace left to come, and United needing to make up six points to Arsenal in fourth, Rangnick urged ‘realism’ about their situation.
He said: ‘I don’t think it makes sense to speak and speculate about the Champions League. We need to be realistic.
‘Even if we win four games, it’s not in our hands. Even for next season, it’s important to finish on the best possible note.’
More to follow.
Source: DailyMail Sports