Donald Trump savaged a ‘seriously overweight’ friend of his who he claims is taking the ‘fat shot drug.’

During the announcement of an executive order aimed at reducing prescription drug costs, Trump shared a tale about a friend from the business sector, expressing frustration over the price differences in weight loss medications between the U.S. and other countries.

He criticized this person, without naming him, in a heated speech concerning the cost of GLP-1 drugs, which he dubbed the ‘fat shot.’

‘Let me tell you a story – a friend of mine who’s a business executive, extremely high-profile, very well-known. Many of you probably know him – highly neurotic, a brilliant but overweight businessman,’ Trump said as he began his story.

‘And he takes the fat shot drug,’ he continued.

This story led to some speculation over who the president was talking about during his remarks from the Roosevelt Room on Monday morning.

Trump’s ‘first buddy’ and outgoing DOGE leader Elon Musk admitted that he is on Mounjaro, one of the popular GLP-1 blood sugar medications that have become popular for their weight loss side effect.

One X user questioned if Musk is the ‘high neurotic’ and overweight businessman that the president was referencing.

Another user wrote: ‘There are 300 fat, neurotic businessmen all over America today beaming fat, neurotic smiles because they all think Trump was talking about them.’

‘This actually is pretty funny,’ an X account noted in sharing a clip of the story. ‘Somewhere out there, a rich man is thinking ‘I’m President Trump’s fat friend.’ 

Trump continued in his White House rant on Monday the story about his rich friend discovering price differences between drugs in the U.S. and foreign nations.

‘And he called me up and he said… ‘I’m in London and I just paid for this damn fat drug I take.’ I said, ‘It’s not working,’ the president joked.

‘He said, ‘I just paid $88 and in New York I pay $1,300.’ What the hell is going on?’ he questioned.

‘He said, ‘So I checked and it’s the same box, made in the same plant, by the same company. It’s the identical pill that I buy in New York.’… Now this is a great businessman, but he’s not familiar with this crazy situation that we have.’

‘But he was stunned. And it was just one of those stories,’ Trump concluded from behind the podium in the Roosevelt Room on Monday.

The president never mentioned the business colleague by name and it’s unclear from the story who he is talking about. 

Some of Trump’s former ‘fat’ friends include one-time Secretary of State Mike Pompeo, who lost 90 pounds in six months.

Additionally, former New Jersey Gov. Chris Christie has lost a significant amount of pounds in recent years, but is still overweight.

Trump placed the blame directly on foreign nations for the price disparities between medicines, claiming drug companies were forced to lower costs for those countries and allowed to keep them higher for Americans.

He said that the U.S. would no longer be ‘suckers’ for the rest of the world.

And he also slammed Democrats for ‘protecting pharma.’

Trump said during an announcement from the White House that his order would target the highly popular GLP-1 fat loss, which he called the ‘fat shot drug.’

‘The weight loss drug Ozempic costs ten times more in the United States than the rest of the developed world. Ten times more. Why? What did we do? Suckers,’ Trump lamented.