US Drug Enforcement Administration Chicago field office touts progress after major fentanyl busts: ABC7 I-TEAM EXCLUSIVE

CHICAGO (WLS) — The ABC7 I-Team spoke exclusively with Chicago’s top drug enforcer, touting progress after several major fentanyl busts.

Sheila Lyons, the Special Agent in Charge of the U.S. Drug Enforcement Administration’s Chicago field office, recently had an open discussion with the I-Team. She shared insights about the future direction of her agency, highlighted significant drug seizures over the last six months, and introduced new strategies her agents are using to tackle the impact of Mexican cartels in Chicago.

ABC7 Chicago is now streaming 24/7. Click here to watch

Vehicles engulfed in flames show the violence perpetrated by vicious Mexican cartels motivated only by money, according to federal authorities.

“They have no regard for human life. They don’t care who dies, gets poisoned, or overdoses,” Lyons explained. “As long as there’s demand, they’ll keep producing, manufacturing, and distributing drugs.”

That potential for bloodshed is spilling across the border and into Chicago communities.

“I believe that these drug trafficking organizations, the cartels that support them, and all the networks they’re involved with, are closely linked to the violence,” Lyons added.

Lyons said in the seemingly never-ending illicit drug crisis, some progress has been made, saying 1.6 million deadly fentanyl pills were seized in the first half of this year in the Midwest region. That’s more than double the amount of last year and more than the last three years combined.

“They don’t have to follow any rules and every idea they come up with,” Lyons said. “They don’t have to worry about budget and they don’t have to worry about the law. They don’t care. So everything’s on the table every time, in terms of moving product from point A to point B.”

Speaking frankly with the I-Team, Lyons described her administration as small but mighty, and one that has been targeted by the Justice Department for a merger with the Bureau of Alcohol Tobacco and Firearms.

“Well, nothing is insurmountable,” Lyons said. “But in terms of merging federal agencies for the betterment of productivity and funding… that’s something that is being socialized at the Department of Justice, and so I have to leave it to those who know a lot more about it than me.”

For now, the battle against cartel influence rages on in Chicago…

A plea deal is expected Friday from Ovidio Guzman Lopez, a former Mexican drug lord of the Sinaloa Cartel and El Chapo’s son.

The Midwest region is a major hub for cartels distributing drugs across the country, according to the DEA.

Eight Mexican cartels have a new designation from the federal government, possibly allowing the DEA to do more to take them down.

“It broadens the amount of information that we will now be able to share and pull in for actionable items throughout the relationships that we have in our federal government entities,” Lyons said.

However, as DEA agents continue their training for battle on Chicago streets, the cocktail of pharmaceuticals flooding the market gets murkier.

“In Chicago right now, the drug threat continues to be of poly-drug origin,” Lyons said.

It’s a complicated combinations of drugs that advocates on the ground simply refer to as “dope” with insatiable demand.

“Manufacturers of those drugs, they’ll just pivot to a different variation or formulation of those drugs, often something that is easier to smuggle, easier to manufacture, and is a little bit more potent,” said John Werning, executive director of Chicago Recovery Alliance. “So if this sounds familiar, it’s because it’s kind of how we got fentanyl in this country.”

Werning’s team at the Chicago Recovery Alliance distributes drug testing strips and clean needles focusing on harm reduction in the community. He said the vast amounts of federal dollars spent on the war on drugs can be better utilized.

“My argument would be, why don’t we put trillions of dollars into programs like treatment, harm reduction, housing access, medical access, which we know have evidence through evidence actually do reduce the demand for those drugs, or at least impact it in a better way,” he said.

Werning said the demand for drugs in Chicago is not abating, and Lyons says with it comes a rise of cocaine and methamphetamine in the region and new, looming dangers.

“There are always emerging drug threats,” Lyons said. “So yes, we are seeing carfentanil. We’re seeing nitazines. We’re seeing xylazine. It’s called a zombie drug. These are serious, dangerous drugs that are emerging throughout the country, and we are seeing them here in the Chicago field division.”

Major busts have deterred and disrupted the dangers but not have dissolved demand.

“These are vicious, greedy people who do not care about public safety or the human condition,” Lyons said. “They don’t care about people. They care about profit.”

Fatal overdose numbers are still high, but they are trending down, and it is something the DEA attributes to education efforts.

Lyons confirmed to the I-Team that DEA agents are assisting with federal immigration actions per orders from the president, but said their core mission has not been affected and that the administration has been just as productive as the last 10 years.

Copyright © 2025 WLS-TV. All Rights Reserved.

You May Also Like
Wife speaks out after husband allegedly strangles disabled daughter to death in New Jersey

New Jersey Wife Breaks Silence After Husband Allegedly Strangles Disabled Daughter to Death

FRANKLIN TWP., N.J. — The family of Devin Hall is now preparing…
Austin Metcalf’s dad supported Karmelo Anthony judge’s hard line on cameras

Jeff Metcalf Breaks His Silence on Son Austin’s Death—How His Family Is Finding Strength and Moving Forward

FRISCO, Texas — Jeff Metcalf, whose son Austin Metcalf was killed in…
South Carolina personal trainer goes missing, last spotted walking toward wooded area

SLED Joins Investigation After Body Found Matches Description of Missing South Carolina Personal Trainer

South Carolina’s lead investigative agency, the State Law Enforcement Division (SLED), joined…
'Pure hell' in Moscow as Ukrainian drones strike major refinery supplying capital's fuel market

Moscow Refinery Hit by Ukrainian Drones, Disrupting Key Fuel Supply to the Capital

Ukraine carried out one of its biggest drone assaults on Moscow since…
Florida couple sues fertility clinic after allegedly giving birth to someone else's baby

Florida Couple Settles With Biological Parents in Alleged IVF Embryo Mix-Up Case

A Florida couple who say a fertility clinic mistakenly implanted the wrong…
Former child actor Daveigh Chase, voice of Lilo from 'Lilo & Stitch' and "The Ring' villain, dies at 35

Daveigh Chase, Voice of Lilo in ‘Lilo & Stitch’ and Star of ‘The Ring,’ Dies at 35

LOS ANGELES — Daveigh Chase, the former child actor best known as…
Luigi Mangione bails on psychiatric defense in UnitedHealthcare CEO assassination case

Luigi Mangione Drops Psychiatric Defense in UnitedHealthcare CEO Assassination Case: What It Means for the Trial

Mangione to use ‘psychiatric defense’ in CEO murder trial, judge says Luigi…
Israel launches 'Biblical Highway' amid campaign to erase Jewish history

Israel’s “Biblical Highway”: New Route Counters Efforts to Erase Jewish History

Israel to inaugurate a new ‘Biblical Highway’ Israel’s government on Tuesday approved…
FBI top 10 fugitive Arnoldo Jimenez, arrested in fatal 2012 stabbing of newlywed Estrella Carrera in Burbank, brought to Chicago

FBI Most Wanted Arnoldo Jimenez Captured: Chicago Fugitive Arrested in 2012 Newlywed Murder Case

BURBANK, Ill. — A man sought by the FBI for more than…
Streator, Illinois City Council approves emergency declaration as tornado recovery continues

Streator City Council Approves Emergency Declaration as Tornado Recovery Efforts Continue

Streator city leaders have unanimously approved an emergency declaration as the community…
Man killed after horse-drawn carriage bolts and flips near popular New York City tourist destination

Man Dies After Horse-Drawn Carriage Flips Near Central Park in New York City

An 18-year-old tourist from India was killed Wednesday after a horse-drawn carriage…
11 suspected illegal immigrants among 15 arrested in $1.4M benefits fraud crackdown in Massachusetts, DOJ says

Massachusetts Benefits Fraud Bust: 15 Arrested, Including 11 Suspected Illegal Immigrants, in $1.4M DOJ Crackdown

Federal authorities brought a nationwide welfare fraud crackdown to Massachusetts this week,…