Row breaks out between international scientists and US health chiefs after they link paracetamol to autism
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Health experts today rebutted ‘dangerous’ assertions that paracetamol increases autism risk, following President Trump’s assertion of having ‘found an answer’ for the condition.

Paracetamol, also known as acetaminophen and often sold as Tylenol in the US, is widely taken by pregnant women for pain relief, headaches, and fever.

Numerous studies have associated it with a higher incidence of autism and attention deficit hyperactivity disorder (ADHD), though findings are frequently inconsistent.

Reports today suggest the US leader, 79, plans to formally establish this connection following a federal review investigating the rising autism rates nationwide.

Medical experts worldwide assert there’s no proven link between the drug and neurodevelopmental disorders, criticizing the announcement as ‘fear mongering’ that ‘risks stigmatising families.’

Dr. Monique Botha, an associate professor in social and developmental psychology at Durham University, stated: ‘There is no robust evidence or convincing studies showing any causal relationship. Any contrary conclusions are often motivated, lack evidence, and aren’t supported by the most rigorous methods to answer this question.’

‘I am exceptionally confident in saying that no relationship exists. 

‘Pain relief for pregnant women is woefully lacking and paracetamol is a much safer pain relief option during pregnancy than basically any other alternative and we need to take pain seriously for women including whilst pregnant. 

President Trump revealed he would be making an announcement about autism during a detour in his speech at Charlie Kirk's memorial service in Arizona on September 21 (pictured)

President Trump revealed he would be making an announcement about autism during a detour in his speech at Charlie Kirk’s memorial service in Arizona on September 21 (pictured)

Dozens of studies have already linked it to higher rates of autism and attention deficit hyperactivity disorder (ADHD). However, the findings have not often been consistent

Dozens of studies have already linked it to higher rates of autism and attention deficit hyperactivity disorder (ADHD). However, the findings have not often been consistent

‘The fear mongering will prevent women from accessing the appropriate care during pregnancy. 

‘It also risks stigmatising families who have autistic children as having brought it on themselves.

‘It reinvigorates the long pattern of maternal shame and blame we’ve seen re-emerge repeatedly over the last 70 years, where we try to pay the fault of autism at the mother’s door one way or another.’ 

Dr Hannah Kirk, a senior lecturer in developmental psychology at Monash University, added: ‘No study has shown that paracetamol causes autism. 

‘Some studies have reported an association between paracetamol use and autism, while others have not. Importantly, association does not mean causation.

‘A recent large-scale study, which analysed data from 2.48 million births, found that when researchers compared siblings—a method to control for genetic and environmental factors—any apparent links between paracetamol and autism disappeared. 

‘This suggests that other factors such as genetic or underlying maternal health conditions may better explain the findings.

‘It’s also worth noting that fever itself has been linked to adverse pregnancy outcomes. 

‘In many cases treating a fever with paracetamol may reduce those risks. 

‘Pregnant people should continue to follow the advice of their healthcare providers when managing pain and fever.’

Professor Stephen Griffin, an infectious disease expert at the University of Leeds, meanwhile said the argument that paracetamol ’causes’ autism ‘lays the blame firmly at the parent’s door. Just unbelievably cruel’.

He added: ‘It’s a complex, polygenic, largely unpredictable syndrome. Fact.’

Professor Dimitrios Siassakos, an expert in obstetrics and gynaecology at University College London also argued: ‘Undue focus on paracetamol would risk preventing families from using one of the safest medications to use in pregnancy when needed.’ 

President Trump revealed he would be making an announcement about autism during a detour in his speech at Charlie Kirk’s memorial service on Sunday.

‘I think you’re going to find it to be amazing. I think we found an answer to autism,’ he added. 

Trump added that his administration ‘won’t let it happen anymore.’

But reports today claim the President Trump will formally make the link following a federal review into what is driving rising rates of autism across the country. The review was launched by US health secretary Robert F Kennedy Jr, pictured during Charlie Kirk's memorial service in Arizona on September 21

But reports today claim the President Trump will formally make the link following a federal review into what is driving rising rates of autism across the country. The review was launched by US health secretary Robert F Kennedy Jr, pictured during Charlie Kirk’s memorial service in Arizona on September 21

‘I think it’s going to be one of the most important news conferences I’ll ever have, and I look so forward to it,’ he said.

It comes as US researchers from Mount Sinai and Harvard’s School of Public Health, last month, suggested that pregnant women should only take paracetamol on the advice of a doctor amid autism fears. 

The scientists said their analysis of more than 100,000 people was the most comprehensive yet—and provided the ‘strongest evidence so far’ of a link. 

They urged mothers-to-be to use paracetamol sparingly, recommending only ‘the lowest effective dose for the shortest possible time.’

However, the team stressed the findings do not prove the drug directly causes neurodevelopmental disorders—only that the association is consistent and worrying enough to demand further investigation.

Dr Diddier Prada, assistant professor of population health science at Mount Sinai Hospital in New York and co-author of the study, said: ‘Given the widespread use of this medication, even a small increase in risk could have major public health implications.

‘Pregnant women should not stop taking medication without consulting their doctors. Untreated pain or fever can also harm the baby. 

‘Our study highlights the importance of discussing the safest approach with health care providers and considering non-drug options whenever possible.’

Paracetamol is currently recommended by the NHS as the ‘first choice’ painkiller for expectant mothers, but only for short periods and at the lowest effective dose.

Around half of pregnant women in the UK take paracetamol, and in the US the figure rises to around 65 per cent. 

Health chiefs advise that only certain people — such as those with liver or kidney disease or taking epilepsy medication — need to exercise extra caution.

NHS figures show almost 130,000 under-18s in England were waiting for an assessment in December 2024.

Experts have described it as an ‘invisible crisis’, with services repeatedly failing to keep pace with rising demand. 

Last year, the Children’s Commissioner warned that children left languishing for years on waiting lists were effectively being ‘robbed’ of their childhoods.

Autism is not a disease and is present from birth, although it may not be recognised until childhood or even much later in life. 

It exists on a spectrum: while some people can live independently with little support, others may need full-time care.

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