UPS plane crash and explosion leaves 9 dead and others missing in Kentucky

Authorities are on a relentless search for more victims following a devastating UPS cargo plane crash that erupted into a massive fireball at the global aviation hub in Kentucky. The tragic incident has claimed the lives of at least nine individuals and left 11 others injured, according to officials.

The plane went down around 5:15 p.m. on Tuesday as it was set to depart from UPS Worldport at Louisville Muhammad Ali International Airport, heading for Honolulu.

Kentucky Governor Andy Beshear took to social media on Wednesday morning, revealing that 16 families at a reunification center reported that their loved ones are still missing.

Fire and smoke mark where a UPS cargo plane crashed near Louisville Muhammad Ali International Airport on November 04, 2025 in Louisville, Kentucky.
Fire and smoke mark where a UPS cargo plane crashed near Louisville Muhammad Ali International Airport on November 04, 2025 in Louisville, Kentucky.Photo by Stephen Cohen/Getty Images

The airport is situated just 7 miles from downtown Louisville, near the Indiana border, surrounded by residential areas, a water park, and museums. Initially, emergency teams issued a shelter-in-place order covering a 5-mile radius, which by Wednesday morning had been reduced to a quarter-mile, as they assessed air quality.

More than 200 emergency personnel responded to the scene on Tuesday night, as confirmed by Louisville Mayor Craig Greenberg.

“We are committed to deploying every available resource to handle this situation,” Mayor Greenberg stated during an interview with WLKY-TV on Wednesday morning.

Video showed flames on the plane’s left wing and a trail of smoke. The plane then lifted slightly off the ground before crashing and exploding in flames. Video showed portions of a building’s shredded roof next to the end of the runway.

Beshear said he didn’t know the status of the three crew members aboard the plane, a McDonnell Douglas MD-11 made in 1991. It wasn’t immediately clear if they were being counted among the dead.

‘We all know somebody who works at UPS’

Beshear said he expects the death toll to increase. Eleven people were also hurt. Beshear said two of the injured are in critical care.

“Anybody who has seen the images, the video, knows how violent this crash is,” he said.

The Louisville package handling facility is the company’s largest, and UPS announced late Tuesday that package sorting at the center was halted. It didn’t say when operations would resume. The hub employs thousands of workers, has 300 daily flights and sorts more than 400,000 packages an hour.

“We all know somebody who works at UPS,” Louisville Metro Council member Betsy Ruhe said. “And they’re all texting their friends, their family, trying to make sure everyone is safe. Sadly, some of those texts are probably going to go unanswered.”

Hoping for information about missing loved ones

Eric Richardson stood outside a police training academy, where people gathered waiting for word of their missing loved ones Tuesday night. He said was hoping for information about his girlfriend, who had been at a metal recycling business near the explosion and wasn’t answering her phone. Her phone’s live location said she was still there.

Bobby Whelan, Richardson’s friend, had been in front of her in line, but had left minutes before the explosion. He said he was about a quarter of a mile down the road when he heard what sounded like a bomb exploding.

“We don’t even want to think about anything but the best,” Whelan said. “All our friends were there.”

The governor said a business, Kentucky Petroleum Recycling, appeared to be “hit pretty directly,” and a nearby auto parts operation was also affected.

Tom Brooks Jr., who runs a metal recycling business down the street, said the unbelievable magnitude of the crash “just rocked the whole place.”

“This was massive. I mean, it literally looked like a war zone,” he said.

Destyn Mitchell was working as a host at an Outback restaurant, about a 15-minute drive from the crash, when she heard a loud boom.

“People who just sat down to eat got up and left in under 30 minutes and packed up their food because they wanted to hurry up and get home,” she said.

What happened to the plane?

Pablo Rojas, an aviation attorney, said that based on videos of the crash the aircraft appeared to be struggling to gain altitude as a fire blazed on its left side around one of its engines. Given the fuel the plane was carrying, it was only a matter of time before the blaze spread rapidly or an explosion happened.

“Really the plane itself is almost acting like a bomb because of the amount of fuel,” he said.

Greenberg said the National Transportation Safety Board has sent a 28-strong crew to investigate the crash.

The airport, which also shut down for the night, resumed operations Wednesday morning, with at least one runway open. Flights that were canceled Tuesday were scheduled to depart and arrive first. Some flights previously scheduled to take off from the airport Wednesday morning were canceled.

Some stranded passengers spent the night in the airport, and nearby roads remained closed Wednesday morning. A public school district in Louisville canceled classes and activities for the day.

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