(WGN Radio) – An over-the-counter nasal spray for allergies could actually protect you from catching COVID, a recent randomized trial found.

Using a nasal antihistamine containing azelastine three times a day for eight weeks has been shown to decrease the occurrence of COVID-19 infections by 69%. Interestingly, the study also noted that individuals who used the nasal spray experienced significantly fewer cases of the common cold (rhinovirus) compared to those in the placebo group.

Dr. Thomas Moran, chief medical officer at Central DuPage Hospital in Illinois, explained how it works in an interview with WGN Radio:

“When considering the reasons for using nasal sprays, we often look at nasal passageway inflammation. This inflammation leads to the deterioration of the mucus membrane. The membrane in our nasal passages serves as a barrier to viruses and bacteria, preventing them from entering our bodies. This nasal spray appears to lower a protein that increases inflammation, making it harder for the COVID virus to invade and impact us.”

Hear more of Dr. Moran’s interview in the audio player below:

Although the initial trial was small, involving 450 participants, it is quite promising due to its simplicity, stated Dr. Robert Bals, who led the trial. This method could offer an easy and cost-effective option for individuals seeking to enhance their defense against respiratory viruses.

“Azelastine nasal spray could serve as an additional readily available preventive measure to support existing protective methods, particularly for vulnerable groups, during times of high infection rates or prior to travel,” Bals mentioned in a press release.

Dr. Moran concurred: “It is relatively safe with minimal side effects—occasionally causing slight congestion—and it is generally affordable to use.”