The passing of Catherine O’Hara at the age of 71 has led to a heartfelt response from her colleagues and friends who cherished her presence over the years. Known for her exceptional comedic talent in classic films such as “Home Alone,” “Schitt’s Creek,” and “Beetlejuice,” O’Hara passed away on Friday in Los Angeles following a brief illness.

Macaulay Culkin

Sharing his grief on Instagram, Macaulay Culkin, who famously played O’Hara’s son in the “Home Alone” series, expressed, “Mama. I thought we had time. I wanted more. I wanted to sit in a chair next to you. I heard you. But I had so much more to say. I love you. I’ll see you later.”

Meryl Streep

Meryl Streep, who starred alongside O’Hara in “Heartburn,” paid tribute with a poignant statement, saying, “Catherine O’Hara brought love and light to our world, through whipsmart compassion for the collection of eccentrics she portrayed…such a loss for her family and friends, and the audience she graced as friends.”

Michael Keaton

“We go back before the first Beetlejuice. She’s been my pretend wife, my pretend nemesis and my real life, true friend. This one hurts. Man am I gonna miss her.” — the actor, on Instagram.

Seth Rogen

“Really don’t know what to say… I told O’Hara when I first met her I thought she was the funniest person I’d ever had the pleasure of watching on screen. Home Alone was the movie that made me want to make movies. Getting to work with her was a true honour. She was hysterical, kind, intuitive, generous… she made me want to make our show good enough to be worthy of her presence in it. This is just devastating. We’re all lucky we got to live in a world with her in it.” — “The Studio” creator and star, on Instagram.

Pedro Pascal

“Oh, genius to be near you. Eternally grateful. There is less light in my world, this lucky world that had you, will keep you, always. Always” — the actor, who worked with O’Hara on the second season of “The Last of Us,” on Instagram.

Kevin Nealon

“Catherine O’Hara changed how so many of us understand comedy and humanity. From the chaos and heart of Home Alone to the unforgettable precision of Moira Rose in Schitt’s Creek, she created characters we’ll rewatch again and again.” — the comedian and actor, on social media.

Craig Mazin

“I think she would prefer that we keep laughing somehow, or at the very least not cry. Not possible at the moment. As brutal as this feels for anyone who knew or worked with her, I know it is far more painful for her husband and sons and close family. I’m thinking about them right now too. It all hurts terribly. Goodbye, you legend… you wonderful, brilliant, kind, beautiful human being. We were lucky to have had you at all.” — the “The Last of Us” showrunner, on Instagram.

Christopher Guest

“I am devastated. We have lost one of the comic giants of our age. I send my love to her family.” — the actor and director, who collaborated with O’Hara on four films, in a statement.

Sarah Polley

“She was the kindest and the classiest. How could she also have been the funniest person in the world? And she was at the very top of her game. There won’t be another like her.” — the Canadian director and actor, on Instagram.

Ron Howard

“This is shattering news. What a wonderful person, artist and collaborator. I was lucky enough to direct, produce and act in projects with her and she was simply growing more brilliant with each year. My heart goes out to Bo & family.” — the actor and director, on Instagram.

Ike Barinholtz

“I never in a million years thought I would get to work with Catherine O’Hara let alone become friends with her. So profoundly sad she’s somewhere else now, So incredibly grateful I got to spend the time I did with her. Thank you Catherine I love you.” — the actor, a co-star in “The Studio,” on Instagram.

Rita Wilson

“Catherine O’Hara — a woman who was authentic and truthful in all she did. You saw it in her work, if you knew her you saw it in her life, and you saw it in her family. Bo, Luke and Matthew, our deepest sympathies. May Catherine rest in peace. May her memory be eternal. — the actor, director and producer, on Instagram.