The streets and neighborhoods around Nancy Guthrie’s Tucson, Arizona, residence became the focal point of an intense FBI search on Wednesday as agents scoured the area for any leads in her disappearance.

The federal agency took to the internet to inform the public about the operation, urging everyone to exercise caution during the search.

“Today, a large number of FBI agents are conducting a thorough search along several roadways in the Catalina Foothills region in connection with the Nancy Guthrie case,” the agency announced. “We request that the media and drivers adhere strictly to traffic regulations and be especially vigilant when passing by law enforcement officials working near the roads.”

Later in the day, a pair of black gloves was discovered about a mile and a half southeast of Guthrie’s residence.

The map indicates the general area where the FBI conducted its search near Nancy Guthrie’s home in Tucson, Arizona, on February 12, 2026. (Fox News Digital)

“There are two likely reasons why they focused on that particular area,” explained Jason Pack, a former FBI Supervisory Special Agent. “Firstly, it offers one of the most straightforward routes for accessing Nancy’s home.”

“Second, there may be digital evidence that prompted investigators to focus there,” he continued. “Now we need to be cautious here because we don’t yet know if the gloves that were recovered are actually connected to this case. But if they are, that’s a significant development.”

Pack said more canvasses can be expected as the investigation into Guthrie’s vanishing continues.

FBI investigators search Catalina Foothills in Tucson, Arizona, on Wednesday, February 11, 2026. The investigations into the disappearance of Nancy Guthrie continues. (DWS for Fox News Digital)

“Expect investigators to set up new canvasses expanding outward from that location, looking for additional cameras along the route from businesses, from homes, anything that may have captured movement,” he said. “And they’ll be expanding the timeline backwards, looking at the hours before and after she went missing. The goal is to build a trail.​​​​​​​​​​​​​​​​”

An individual seen on doorbell footage from Guthrie’s home, also released by the FBI, was covered head to toe in a ski mask, jacket, pants and gloves.

This image released by the FBI shows an armed individual appearing to have tampered with the camera at Nancy Guthrie’s front door the morning of her disappearance in Tucson, Arizona, Sunday, February 1, 2026. (Provided by FBI)

Guthrie was last seen on the night of Jan. 31, and authorities suspect she was abducted from her home early the next morning.

No suspects have been named.