JERUSALEM – A few hours following President Donald Trump’s wrap-up of his Middle East tour, Iran’s Ayatollah Ali Khamenei unleashed a verbal attack on America and Israel, accusing Trump of being deceitful and advocating for the elimination of the Jewish nation.

“Trump claims he desires to wield power for peace, which is false,” Khamenei stated on X, further commenting, “Certain statements made during the US President’s regional visit do not even merit a reply. Their insignificance is such that they bring embarrassment to the American populace.”

Since the 1980s, the US has labeled Iran as a state sponsor of terrorism. The intensely anti-Western and antisemitic leader referred to Israel—America’s principal partner in the Middle East—as a “cancerous tumor” that ought to be eradicated.

According to the Trump administration, Khamenei’s regime is the world’s leading state-sponsor of antisemitism.

During his trip to Saudi Arabia, the United Arab Emirates and Qatar, Trump called Iran’s regime the main force of instability in the Middle East.

 “The biggest and most destructive of these forces is the regime in Iran, which has caused unthinkable suffering in Syria, Lebanon, Gaza, Iraq, Yemen and beyond, “said Trump in the Kingdom of Saudi Arabia.

Alireza Nader, a Washington, D.C., expert on Iran’s regime, told Fox News Digital that Iran “has been dealt a severe military setback by Israel, and the Iranian public desires the regime’s overthrow. President Trump has an overwhelming advantage in the negotiations and could severely restrict and limit the regime’s nuclear program.”

Trump said he wants a deal with Iran to stop its illegal nuclear weapons program. In his speech, Trump told Iran that it must abandon its drive to build an atomic bomb.

“While you have been constructing the world’s tallest skyscrapers in Jeddah and Dubai, Tehran’s 1979 landmarks are collapsing into rubble,” Trump said. “[Iran’s] corrupt water mafia . . . causes droughts and empty riverbeds. They get rich.”