3 children die from diphenhydramine overdoses, antihistamine sold as Benadryl amid social media trend

In Stamford, Connecticut, three children have tragically lost their lives in the last two months due to overdoses of diphenhydramine, an antihistamine widely known under the brand name Benadryl. This information was confirmed by the state’s Office of the Child Advocate.

“The number of cases is alarming and definitely warrants attention,” commented Dr. Krishnan Narasimhan, who leads the family medicine department at Stamford Hospital.

While diphenhydramine has been a staple in allergy treatment, many medical professionals are now opting for more modern alternatives, moving away from this older medication.

Dr. Narasimhan highlighted the potential drawbacks of the drug, emphasizing its side effects.

“It has numerous side effects and can cross the blood-brain barrier, often leading to considerable sedation for those who take it,” he explained.

The state has withheld specific details about the victims’ ages and locations. Additionally, there has been no official connection made between these deaths and the “Benadryl Challenge,” a dangerous social media trend that initially gained notoriety in 2020 and occasionally resurfaces.

“This has been going on for years, starting with the Tide Pod Challenge, the cinnamon challenge. There’s so many things that we’ve talked to them for years and years about not doing any of these things, and they’re even considering it to talk to us first,” Stamford parent Michele Hayes said.

The challenge encourages participants to take as many as 24 tablets in 24 hours to induce hallucinations, which are then recorded and posted online.

That amount is double the recommended adult dosage and, according to doctors, can impair breathing to the point of coma and cause other toxic effects.

“You can get severely agitated. You can have extra heartbeats. Which can lead to cardiac complications and actually can lead to cardiac arrest and death,” Narasimhan said.

Doctors advise families to secure all medications.

A family friend of one victim told ABC New York affiliate WABC that a 13-year-old girl in Waterbury had Benadryl delivered through DoorDash without an ID check.

The deaths remain under investigation.

Copyright © 2026 WABC-TV. All Rights Reserved.

Leave a Reply

Your email address will not be published. Required fields are marked *

You May Also Like

DFW Airport Cancels Planned Muslim Foot-Washing Stations After Texas Governor Pushback - Internewscast Journal

DFW Airport Cancels Planned Muslim Foot-Washing Stations After Texas Governor Pushback

Texas Gov. Greg Abbott is facing mounting political pressure at home —…
Florida Cold Case Suspect Allegedly Confesses to 1987 Murder, Reveals Hidden Crime Scene Details - Internewscast Journal

Florida Cold Case Suspect Allegedly Confesses to 1987 Murder, Reveals Hidden Crime Scene Details

A Florida man accused in the 1987 killing of a young mother…
Dire reports of USS Abraham Lincoln conditions dismissed

Navy Dismisses Dire Claims About USS Abraham Lincoln Conditions

Acting Navy Secretary Hung Cao praised the crew of the USS Abraham…
Kolthoum Akbari: Iran’s Black Widow Faces Death Sentence - Internewscast Journal

Kolthoum Akbari: Iran’s Black Widow Faces Death Sentence

Her last appointment is set to be with the executioner. Kolthoum Akbari,…
Texas police shoot gunman who fired at vehicles in Houston

Houston Police Shoot Gunman Accused of Firing at Vehicles

A gunman accused of randomly shooting at vehicles in Houston, wounding three…
Luigi Mangione Pleads Guilty in UnitedHealthcare CEO Shooting Case - Internewscast Journal

Luigi Mangione Pleads Guilty in UnitedHealthcare CEO Shooting Case

NEW YORK — Luigi Mangione acknowledged in federal court Friday that he…
Luigi Mangione Pleads Guilty in Brian Thompson Killing Case - Internewscast Journal

Luigi Mangione Pleads Guilty in Brian Thompson Killing Case

Luigi Mangione tells judge he will plead guilty to federal charges Luigi…
Oakland Deploys Massive Street-Cleaning Machine to Tackle Illegal Dumping - Internewscast Journal

Oakland Deploys Massive Street-Cleaning Machine to Tackle Illegal Dumping

Oakland is turning to heavy-duty equipment as it works to tackle the…
Iran Jails Psychologist Over Trump Plea, Family Alleges - Internewscast Journal

Iran Jails Psychologist Over Trump Plea, Family Alleges

Seyed Ahmad Seyedabdollahi, a 32-year-old psychologist and counselor from Borujen who had…
Man Charged With Hate Crimes After NYC Synagogue Disruption - Internewscast Journal

Man Charged With Hate Crimes After NYC Synagogue Disruption

A Bronx man is facing multiple hate crime charges after police say…
Chicago Weather: Air and Water Show Delayed; NIPSCO Crews Paused - Internewscast Journal

Chicago Weather: Air and Water Show Delayed; NIPSCO Crews Paused

CHICAGO () — NIPSCO temporarily halted some storm restoration work in northwest…
9/11 Docuseries Reveals How Squeegee Saved Six in Elevator - Internewscast Journal

9/11 Docuseries Reveals How Squeegee Saved Six in Elevator

When al-Qaeda terrorists attacked the World Trade Center on Sept. 11, six…