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The notorious Sinaloa Cartel’s Tijuana Plaza has long been under the control of René “La Rana” Arzate-García and his brother, Alfonso “Aquiles” Arzate-García. Recently, a new indictment has been unveiled, accusing these influential figures of orchestrating the trafficking of vast quantities of drugs into the United States.
In a bid to apprehend the brothers, the U.S. State Department is offering a substantial reward of up to $5 million for information that could lead to their capture.
René Arzate-García faces serious charges, including narco-terrorism, operating a continuous criminal enterprise, and providing material support to a foreign terrorist organization. He is also accused of international conspiracy to distribute methamphetamine, cocaine, fentanyl, and marijuana, alongside money laundering activities.
For the past 15 years, the Arzate-García siblings have effectively managed the Tijuana Plaza for the Sinaloa Cartel. Their grip on power is maintained through a blend of violence, strategic partnerships, and significant local influence, which extends to political and police corruption, as reported by the Drug Enforcement Administration (DEA).
Despite persistent conflicts, the brothers have retained control over this crucial trafficking route, cementing their roles as pivotal players in the cartel’s operations. Among the drugs smuggled under their watch is the lethal fentanyl, which was notably classified by the Trump administration as a “weapon of mass destruction,” posing a grave threat to U.S. communities.

René Arzate-García remains a wanted man, with numerous charges hanging over him, including narco-terrorism.
Court documents allege La Rana uses paramilitary fighters to patrol and control territory, as well as drones equipped with explosives to conduct surveillance.
Officials said his group also has an extensive collection of military grade and high-powered guns and weapons, including assault weapons and grenade launchers.
“Foreign terrorist organizations like the Sinaloa Cartel have spent decades poisoning our children and committing acts of unimaginable violence against innocent civilians — no longer under President Trump,” Attorney General Pam Bondi wrote in a statement.

Alfonso Arzate-García is wanted for conspiracy to distribute meth and marijuana. (Department of Justice)
“This latest indictment, which follows the landmark conviction of Sinaloa Cartel co-founder ‘El Mayo’ on American soil, is a key development in this Department of Justice’s ongoing campaign to permanently dismantle these cartels and deliver American justice to their cowardly leaders,” she continued.
Last year, Trump designated the Sinaloa Cartel as both a foreign terrorist organization (FTO) and a specially designated global terrorist (SDGT).

The DOJ shared photos of weapons allegedly linked to the case. (Department of Justice)
The Arzate-García brothers were charged in the Southern District of California in 2014 with drug trafficking offenses in separate indictments and have been fugitives since that time.
In August 2023, the brothers were designated by the Department of the Treasury’s Office of Financial Assets Control under an executive order.
FBI Director Kash Patel said his agency and its partners have an “unwavering” commitment to thwarting the Sinaloa Cartel.
“We will continue to use everything at our disposal to disrupt their operations and prevent further drugs and violence from coming into our communities,” Patel wrote in a statement. “The Sinaloa Cartel, including its leaders, will be forced to face the consequences of their actions.”
