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A woman was going east in the westbound lanes about 3:30 a.m. when she hit another vehicle at westbound mile marker 5. The woman died, and the man is seriously injured, police said.
All westbound lanes are closed from Cline Avenue to Calumet Avenue and are expected to remain closed for several hours.
Traffic is being diverted at Exit 10 (Cline) and Exit 17 (Gary East).
Emergency crews are on the scene.
Drivers in the area should expect delays and seek alternate routes.
About 1 mile of traffic has become stuck behind the crash investigation, and two badly damaged vehicles could be seen on the road.
State police did not immediately provide any identifying information about those involved in the fatal crash.
This is a developing story; check back with ABC7 Chicago for updates.
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