The human body contains more than 3,600 synthetic toxins, a new report has warned, with chemical exposure now posing a ‘threat to humans.’

An eight-month study conducted by Deep Science Ventures, headquartered in London, delved into the issue of ‘how pervasive toxicity threatens human and planetary health,’ resulting in several concerning findings.

The investigation revealed that the industrial economy has introduced over 100 million artificial chemicals, with an estimated 40,000 to 350,000 actively utilized in commerce today, and chemical production has increased by fifty times since the 1950s.

Over 3,600 synthetic chemicals from food contact materials alone are found in human bodies, 80 of which have hazard properties of ‘high concern’.

According to the report, there is a connection between these toxic chemicals and numerous health issues, including cancer, obesity, Alzheimer’s disease, problems during pregnancy, ADHD, fertility issues, heart diseases, and respiratory problems.

Researchers noted a dramatic rise in cancer rates over recent decades, with early onset cancer in individuals younger than 50 having surged by 79 percent from 1990 to 2019.

They highlighted a potential cause by identifying PFAS, known as ‘forever chemicals,’ present in nearly every human subject tested. Notably, 14 percent of European teenagers have blood concentrations high enough to pose a risk of negative health effects.

And men with high levels of certain PFAS have been found to have less than half the normal sperm count of those with low levels.

Among the findings, it was discovered that the industrial economy has generated over 100 million non-natural chemicals, with between 40,000 and 350,000 being actively used in the market (stock photo).

PFAS, or per- and polyfluoroalkyl substances, are microscopic substances that take thousands of years to break down in the environment and human body, earning them the name ‘forever chemicals.’

Their main purpose is to repel water and oil, which is what makes non-stick cookware easier to clean and why certain jackets and tents can withstand rain.

The chemicals can seep into the water supply from washing dishes and can enter food if packaging is made to be grease-resistant or if the non-stick coating on pots and pans begins to deteriorate.

PFAS are also common in pesticides used on crops, which produces chemical-rich runoff that can enter the drinking water supply. 

From an analysis of peer-reviewed scientific papers as well as interviews with researchers, non-profit leaders, entrepreneurs and investors, the researchers found the food and agricultural industries to be the worst offenders. 

They explain: ‘Pesticides and fertilizers can pollute water and affect local ecosystems as well as the food we eat, and one of the most dangerous fertilizers is the sewage sludge from wastewater treatment plants which is spread on fields even though it often contains many toxic chemicals.’

The researchers warn that PFAS have now ‘contaminated the whole world’, with levels in rainwater often exceeding safe limits for drinking water. 

Last year, the EPA set the maximum contaminant levels for PFAS at 4.0 parts per trillion. 

PFAS exposure can contribute to diabetes development through several mechanisms, including disrupting cells in the pancreas responsible for regulating blood glucose levels, increasing insulin resistance, and potentially increasing body fat

Microplastics smaller than one micrometer, known as nanoplastics, are of most concern as research has shown they can infiltrate cells 

They note that despite the current level of evidence, there are still ‘noticeable gaps’ in how industry and regulatory bodies address chemical toxicity. 

In the US, they highlight how loopholes in regulation have allowed more than 200 new food additives into the food system without undergoing pre-market approval. 

One report by the Environmental Working Group (EWG) reveals that the number is closer to 900 and these additives get through the system through what is referred to as the ‘generally recognized as safe,’ or GRAS, loophole. 

‘The loophole lets those companies – not the FDA – decide when a substance is safe,’ the expose notes. 

It adds: ‘For the other 863 new food chemicals added to the food supply since 2000, food chemical companies exploited the GRAS loophole so they could make their own safety determinations.’ 

The Deep Science Ventures report reveals that in the FDA’s own database, almost 80 percent of chemical additives directly added to food ‘lack the relevant information needed to estimate the amount that consumers can safely eat, and 93 percent lack reproductive or developmental toxicity data.’ 

And of the FDA-regulated additives – both directly and indirectly allowed in food – almost two-thirds don’t have publicly available data. 

In the EU, even with a ‘precautionary ethos, typically based on the ‘no hazard data, no market’ principle’, they say there are still too many exceptions. 

‘The majority of commonly used chemicals lack adequate public data for their long-term health and environmental impacts,’ they add. 

While humans can’t see chemicals and microplastics with the naked eye, research is increasingly showing they have a big impact on our health.

PFAS is a common contaminant in many household items from cookware to toilet paper

These toxins are estimated to cost the US healthcare system about $290 million per year, as they have been linked to everything from birth defects to cancer, dementia to asthma, and infertility to children’s behavioral and learning difficulties.

Microplastics smaller than one micrometer, known as nanoplastics, are of most concern, as research has shown they can infiltrate cells. 

Studies have revealed that microplastics can cause DNA damage and changes in gene activity, known for triggering cancer.

Off the backs of the findings, the researchers called for policy makers and industry leaders to take immediate action. 

Underscoring the need for immediate action, the researchers concluded: ‘Based on our findings, failure to act decisively will likely lead to irreversible consequences for both human health and the delicate balance of our planet’s ecosystems.

‘Policymakers should consider the impact of toxicity on fertility especially as many countries are struggling to boost it using expensive other incentives. This is important because human and planetary health is at stake. 

‘For us to ensure our continued development and ability to thrive as a human species, we have to accelerate the growth of innovative, technological solutions and ensure these are funded and scaled at pace.’