3.9k Share this

Covid is characterised by certain symptoms and its transmissibility rate; however, the course of the disease varies greatly. From lung injury to blood clots, the battle with COVID-19 is more challenging for some. Fortunately, research keeps looking into medicines that can aid recovery and reduce potential damage.

New research shows promising results of an “old” drug that has been used for more than 70 years.

Approved by the U.S. Food and Drug Administration, this drug may protect against lung injury and the risk of blood clots, according to researchers at Weill Cornell Medicine and Cold Spring Harbor Laboratory.

This is especially meaningful for those who might be suffering from a severe disease caused by coronavirus.

The drug in question is called disulfiram.

READ MORE: Cancer symptoms: Two signs to spot when going to the toilet – seen in 90% of patients 

Disulfiram taken orally comes as a tablet and it’s only available on prescription.

This “old” medicine is used for helping to overcome a drinking problem.

It doesn’t represent a cure for alcoholism but it can help discourage you from drinking.

However, there might be more to this tablet.

DON’T MISS:

The preclinical study found that the drug was able to protect rodents from immune-mediated lung injury during infection with the SARS-CoV-2 and a different condition.

The research explains how the tablet works: “Both types of lung injury are now known to be driven in part by immune cells’ formation of web-like structures called neutrophil extracellular traps, or NETs.

“These can trap and kill infectious organisms, but can also be harmful to lung tissue and blood vessels, causing the accumulation of fluid in the lungs and promoting the development of blood clots.

“Disulfiram blocks one of the steps in NETs formation.”

The reason for this is that disulfiram is able to interfere with a molecule needed to produce NETs called gasdermin D.

This means that no NETs are formed after disulfiram treatment, according to the research.

This finding prompted the researchers to test the drug as a NET blocker.

Dr Schwartz said: “Currently, there aren’t any good treatment options for COVID-related lung injury, so disulfiram appears to be worth investigating further in this regard, particularly in severe COVID-19 patients.”

However, there might be some limitations as the research reports that they looked at the form of Covid which was “less severe” than the worst human cases.

They add that disulfiram treatment a day before, or a day after getting infected, leads to “favourable outcomes”.

The researchers saw less NET formation and less scar-like tissue formation in the lungs.

The research added: “By comparison, the standard severe COVID-19 treatment dexamethasone, an immune-suppressing steroid drug, did less to protect lung tissue from disease-related changes, and led to higher levels of SARS-CoV-2 in the lungs.”

What’s more, different research is currently being done on Covid patients to confirm these results.

Source: Daily Express

3.9k Share this
You May Also Like

Bowel cancer symptoms: New M&S campaign to raise awareness of the signs

“And by working with Bowel Cancer UK, we can get the message…

White House to EXPAND use of Pfizer antiviral drug Paxlovid

The White House is planning the expand use of Paxlovid, Pfizer’s antiviral…

Heart disease: Three foods you should cut down on or risk heart attack and failure

The condition will limit the activities you are able to do and,…

Thousands left with dry skin, irritated eyes and burning throat after drinking contaminated water

Thousands of people in Hawaii were left with dry skin, irritated eyes…

Ovarian cancer signs: The seemingly ‘minimal symptoms’ to be aware of – expert

He said: “If you have any of these symptoms that are persistent…

You really CAN die of heartbreak: Widower of Texas teacher shot dies from medical phenomenon

The family of a widower whose wife was shot dead in the…

Monkeypox: Sufferer’s ‘flu-like’ symptoms included dizziness and nausea

When it comes to the tell-tale rash, this sign tends to appear…

Pharmaceutical giant CVS to stop filling out prescriptions for telehealth company Cerebral 

In another setback for the budding, yet controversial, telehealth mental health company…