A tragic incident at a San Francisco hospital resulted in the death of a man, prompting federal immigration authorities to criticize California’s sanctuary laws and the Biden administration’s border policies as contributing factors.

U.S. Immigration and Customs Enforcement (ICE) is appealing to Governor Gavin Newsom and state officials to retain custody of the suspect, a Venezuelan national unlawfully present in the U.S., who had been previously apprehended and released by Border Patrol.

Wilfredo Jose Tortolero-Arriechi stands accused of the fatal stabbing of 51-year-old Alberto Rangel at Zuckerberg San Francisco General Hospital on December 4. Rangel passed away from his wounds two days later, on December 6.

The Department of Homeland Security reports that ICE has issued a detainer request to ensure Tortolero-Arriechi remains in detention, a request complicated by California’s ongoing conflicts with federal immigration authorities.

Alberto Rangel, 51, succumbed to his injuries following a stabbing incident at Zuckerberg San Francisco General Hospital on December 4, 2025. (Department of Homeland Security)

“Were it not for the Biden administration’s irresponsible open-border policies, Alberto Rangel might still be with us,” Acting Assistant Secretary Lauren Bis stated, linking the tragedy to the federal stance on immigration. She urged Governor Newsom to prevent the suspect’s release, condemning sanctuary policies that she claims “endanger American lives.”

The suspect had reportedly displayed alarming behavior in the weeks leading up to the attack, allegedly threatening hospital staff and his own doctor before the deadly stabbing unfolded.

Wilfredo Jose Tortolero-Arriechi, a Venezuelan national in the U.S. illegally, is charged in the fatal stabbing of Alberto Rangel at a San Francisco hospital. (Department of Homeland Security)

Federal officials say Tortolero-Arriechi was first encountered by U.S. Border Patrol in 2023 and then released into the country. The case is adding new fuel to the fight over California’s sanctuary policies.

Earlier this year, ICE revealed that more than 33,000 criminal illegal immigrants are currently in custody across California with active detainers, including individuals accused or convicted of serious crimes such as homicide, sexual assault and drug trafficking.

Despite that, officials say thousands have been released.

Since January 2026 alone, California jurisdictions have declined to honor ICE detainers in more than 4,500 cases, according to the agency. Those releases included individuals tied to dozens of homicides, hundreds of assaults and a wide range of other violent and drug-related offenses, ICE said.

The latest push from federal officials builds on earlier warnings. In February, Acting ICE Director Todd Lyons sent a letter to California Attorney General Rob Bonta urging him to “put the safety of Americans first” by honoring detainers for more than 33,000 criminal illegal immigrants in state custody.

Lyons warned that “no community serious about keeping its residents safe will tolerate a clear aberration of the law,” pressing California officials to cooperate with ICE and take “the worst of the worst off the streets.”

Meanwhile, Alberto Rangel’s death is now being used by federal officials to underscore what they argue are the real-world consequences of those policies.

California Democratic Gov. Gavin Newsom is being criticized by angel mother Agnes Gibboney (far right), whose son, Ronald da Silva, was killed by an illegal immigrant gang member in 2002. (Carlin Stiehl/Los Angeles Times via Getty Images; White House)

Newsom’s office pushed back on that characterization, saying the state’s approach prioritizes accountability and public safety.

“If someone commits a serious crime, they should be held accountable in our justice system,” a spokesperson for Newsom’s office told Fox News Digital. “Allowing someone to evade responsibility simply by being deported undermines the rule of law and completely disrespects the victims harmed by that crime. Our focus must always be to ensure those who commit violent acts face their consequences here.”

A Department of Homeland Security spokesperson told Fox News Digital on Jan. 20, 2026, that a criminal illegal alien allegedly weaponized his vehicle to ram law enforcement officers in Compton, Calif., in an attempt to evade arrest. (KTTV)

The governor’s office also pointed to California’s record of cooperating with federal immigration authorities in certain cases, noting that, since 2019, the state has coordinated the transfer of more than 12,000 individuals, including those convicted of serious and violent crimes, into ICE custody.

Officials added that state law allows coordination with ICE for individuals convicted of serious felonies or those facing credible charges, and said California does not interfere with federal immigration enforcement.

They also argued that federal authorities do not always take custody of individuals when detainers are issued, claiming ICE fails to pick up roughly one in eight people released from state prisons who have immigration holds.

Tortolero-Arriechi remains in custody at the San Francisco County Jail, where he faces homicide and weapons charges, as pressure mounts on California leaders over whether they will comply with federal requests to keep him there.

In a statement issued after his death in December 2025, SEIU Local 521 Chief Elected Officer Riko Mendez said, “Our hearts are with the family, friends, and coworkers of Alberto Rangel,” remembering him as a dedicated social worker.