Here's what we know about a mysterious substance tied to 3 deaths, 18 quarantined first responders in New Mexico


Over a dozen emergency personnel rushed to a grim incident in rural New Mexico, encountering an unidentified substance within the premises.

WASHINGTON — Authorities in New Mexico are currently probing a mysterious material thought to have played a role in the deaths of three individuals, which subsequently led to the temporary quarantine of several first responders.

On Thursday, two individuals remained hospitalized, including one discovered unconscious in a Mountainair residence, a rural area east of Albuquerque, where the fatalities occurred.

Officials were dispatched to the location on Wednesday following reports of a potential drug overdose.

Some responders began exhibiting symptoms such as coughing, vomiting, and dizziness, as per the authorities. Consequently, medical staff evaluated nearly two dozen people who might have been exposed to the enigmatic substance, according to the University of New Mexico Hospital.

The exact nature of the substance remains unknown, as does the cause of death for the individuals in the home and the illness affecting some responders. The number of those showing symptoms is also unclear. Autopsies are planned, and authorities are conducting tests to identify the substances present in the residence.

Here’s what to know about deaths and the investigation.

First responders were decontaminated

Antonette Alguire, a volunteer firefighter in Mountainair, said Wednesday that she saw some EMTs and firefighters coughing, and vomiting after they were outside the house.

Medical workers decontaminated nearly two dozen people, most of them first responders, the University of New Mexico Hospital said. Most of the people had no symptoms, hospital officials said.

Three people were admitted to the hospital Wednesday. One — an emergency medical services official — has since been released, the mayor of Mountainair said Thursday.

Audio reveals some at the home weren’t breathing

Audio archives from the Torrance County Fire Dispatch channel on the site Broadcastify reveal that dispatchers went to the home Wednesday morning, responding to a report of a 60-year-old man who was unconscious but breathing. It was unclear who had made the report.

Within minutes, a dispatcher is heard saying there were three people at the home and two might not be breathing. Then came a call for naloxone, the opioid-overdose antidote.

Torrance County Sheriff David Frazee told The Santa Fe New Mexican that one person was revived using naloxone, which only reverses overdoses in people who have opiates in their systems.

Less than an hour after the initial call, the dispatch center relays that there have been multiple exposures, but there’s no clarity about what substance they were exposed to at the house.

Drugs were found in New Mexico home

Mountainair Mayor Peter Nieto said he spotted drugs at the home, but did not say what type of drugs.

He dismissed carbon monoxide or natural gas exposure as possible causes for the health issues that the first responders experienced.

New Mexico State Police spokesperson Wilson Silver said there was no threat to the public and that investigators do not believe the mysterious substance was airborne.

New Mexico has a high number of overdoses

New Mexico had the fourth-highest rate of drug overdose deaths of any U.S. state in 2024, with 775 deaths, according to the most recent data available by the Centers for Disease Control and Prevention.

Residents around Mountainair, a town with less than 1,000 people, have voiced frustration about drug use in the community and elsewhere.

The mayor posted on social media that the town’s law enforcement officers and first responders work daily to protect the community and respond to difficult situations.

Montoya Bryan reported from Albuquerque. Associated Press writers Claudia Lauer in Philadelphia and John Seewer in Toledo, Ohio, contributed.

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