In a dramatic turn of events on Friday night, authorities conducted a significant search at a residence in Rio Rico, Arizona, a community near the Mexican border. This marks the first search outside properties owned by Nancy Guthrie’s family in the ongoing investigation into her disappearance.

The operation was carried out by the Pima County Sheriff’s Department in conjunction with the FBI. They targeted a house where Carlos Palazuelos was residing. Palazuelos was temporarily detained for questioning during this process.

By early Wednesday morning, investigators had wrapped up their search and departed from the scene.

Up until Tuesday night, searches had been confined to properties belonging to Nancy Guthrie and her eldest daughter, Annie.

A map, featured on Fox News Digital, highlights the three locations scrutinized in connection with the Nancy Guthrie missing person case.

On Sunday, February 1, authorities searched Nancy’s residence following reports that she failed to attend her regular group gathering. This meetup is where she usually participated in a livestreamed church service with friends.

In the evening hours of Friday, Feb. 6, the FBI returned to Nancy’s home, cleared the media away and searched the property again, including on the roof.

A Fox News drone captured an agent appearing to remove a white cylindrical device from a ledge overlooking a courtyard on the property. Authorities later removed a blue SUV from Guthrie’s garage and towed it to an impound lot.

A large police presence outside a residence in Rio Rico, Arizona, on Tuesday, February 10, 2026. (Dario Alequin for News Digital)

Annie Guthrie’s home has also been searched twice, once on Wednesday, Feb. 4, three days into the investigation, and again on Saturday, Feb. 7.

Authorities also stopped by the home briefly on Feb. 6, around the same time as the second search at Nancy’s property. They briefly viewed the side yard on the property and then left.

The Feb. 7 search, which NBC’s Tom Winters reported was “consented to,” was intensive. Investigators entered the home with what appeared to be a white suitcase and a brown bag, and stayed on the property from about 8:00 p.m. to 10:30 p.m.

An investigator arrives at the home of Annie Guthrie in Tuscon, Arizona, on Wednesday, February 4, 2026. Nancy Guthrie has been missing since last being seen on Saturday night. (Derek Shook for Fox News Digital)

Authorities have also conducted multiple extensive searches in both Nancy and Annie’s neighborhoods. The latest canvassing effort took place Tuesday evening, as the FBI went door-to-door in Annie’s neighborhood. 

That effort came on the heels of the first major update in the case. 

FBI investigators canvass the neighborhood around Annie Guthrie’s home in Tucson, Arizona, on Tuesday, February 10, 2026. The investigation into the disappearance of her mother, Nancy Guthrie, continues. (DWS for Fox News Digital)

On Tuesday afternoon, FBI Director Kash Patel released images and video from a doorbell camera on Nancy’s property showing a masked individual covered head-to-toe, wearing a backpack, gloves and armed with a firearm, approaching the home’s entrance.

There are still no suspects in the case.