Nancy Guthrie sheriff defends pace of investigation more than 4 months into search

The Pima County Sheriff, Chris Nanos, has attributed the prolonged investigation into Nancy Guthrie’s suspected abduction to the complexities of lab work, scientific protocols, and the judicial process. This investigation has now extended into its fourth month. During an interview with local media this week, Nanos explained the challenges faced in the case.

“It’s not as simple as sending a detective to interview someone and then making an arrest,” Nanos told Tucson’s KOLD-TV. “This case is particularly sensitive, and the reliance on laboratory analyses is a significant factor in the delay.”

The investigation heavily depends on DNA and digital testing from lab work, which has proven crucial, Nanos added.

Although the interview was broadcast on Monday, a representative from the sheriff’s office clarified to News Agency that the conversation had taken place “several weeks ago.”

A split image shows Sheriff Chris Nanos addressing reporters about the case, alongside a photo of Nancy Guthrie engaged in a game of mahjong. (Credit: Rebecca Noble/Reuters, Courtesy of NBC)

“This investigation remains active and ongoing,” the spokesperson stated. “Forensic analysis of DNA and video evidence is still in progress. Any significant developments in the case will be communicated to the public.”

In a controversial move that stemmed from a public rift with the FBI, 11 weeks after he sent hair samples from Guthrie’s home in the Catalina Foothills to a private genetics lab in Florida, they were forwarded to the bureau’s Quantico lab for more advanced testing. There were also early reports of mixed DNA samples, which are difficult to isolate, and ongoing digital forensic analysis.

“When you’re looking at those labs and the work they do, you have a science there, and science has rules that it has to go by,” Nanos said in his local news interview. “Even though it’s not — DNA they’ll tell you isn’t an exact science — it’s 99% plus. So it’s pretty close, but you still have to follow rules.”

In addition to scientific protocols, there are also rules for the judicial system, he said.

Chris Nanos speaks in the Pima County Sheriff’s Department in Tucson, Arizona, on Friday, May 8, 2026. (Matt Symons for News Agency)

“If I were to say there’s a positive to this, it is that people are working, doing their best to stay within those rules so that they have that understanding that, look, nobody wants to arrest the wrong person,” he said. “We wanna make sure that DNA doesn’t just identify a suspect. It also exonerates those who are innocent.”

Although his office declined to answer questions about who outside the family may have been ruled out or remains a person of interest, Nanos told News Agency last month that detectives were making progress in the case. However, no suspects have been publicly identified, no arrests have been made, and Guthrie’s whereabouts remain unknown.

“The sheriff needs to give us concrete answers on what is going on and what he is doing, not vague platitudes about the scientific process,” said RJ Dreiling, a California criminal defense attorney who is following the case.

“The Guthrie kidnapping has captivated the country — not just because of how well known Ms. Guthrie’s daughter is, but because if this loved and respected woman can be ripped out of her home, and we can’t find the person who did it,” Dreiling told News Agency. “It makes us all wonder how safe are we all really?”

Savannah Guthrie poses with her mother Nancy Guthrie during a production break while hosting NBC’s “Today” show live from Australia. (Don Arnold/WireImage)

While Nanos pointed to forensic testing as a reason for the slow pace of the investigation, federal sources familiar with the probe told News Agency over the weekend that the FBI is discussing deploying new technological tools in the case.

Morgan Wright, the CEO and founder of the National Center for Open and Unsolved Cases, said he believes the new tools are likely focused on one of three areas, all of them digital.

“The solution to this case is going to be, I think, something technical, something that they come up with — new ways of analyzing data,” he told News Agency. “I’m looking at the video, the video forensics, signals analysis, blockchain kind of stuff.”

A woman walking her dog past a Pima County Sheriff's Office patrol car outside Nancy Guthrie's home in Tucson

A woman walks her dog past a Pima County Sheriff’s Office patrol car outside the home of Nancy Guthrie in Tucson, Ariz., on Feb. 8, 2026. (Rebecca Noble/Getty Images)

The investigative genetic genealogy process remains ongoing, and could also crack the case, he said.

Guthrie is the 84-year-old mother of “Today” co-host Savannah Guthrie.

There is a combined reward of over $1.2 million for information that cracks the case, which remains unclaimed.

The family is asking anyone with information to dial 1-800-CALL-FBI. Anonymous tips can be called into Tucson’s 88-Crime hotline at 1-520-882-7463.

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