The United States military executed a lethal strike on Monday aimed at individuals suspected of being cartel operatives in the Eastern Pacific, resulting in the deaths of two individuals linked to drug trafficking, according to reports from the U.S. Southern Command (SOUTHCOM).

“We are committed to applying total systemic friction against the cartels,” SOUTHCOM stated in a social media post. Under the orders of General Francis L. Donovan, commander of SOUTHCOM, Joint Task Force Southern Spear launched a targeted strike on a vessel operated by organizations designated as terrorist groups on April 13.

The intelligence gathered confirmed that the vessel was traversing well-known cocaine-smuggling routes in the Eastern Pacific and was actively involved in narcotics operations. During this decisive action, two male operatives, labelled as narco-terrorists, were killed, while no U.S. military personnel were injured.

This recent strike follows closely on the heels of similar operations conducted by SOUTHCOM just two days prior against other vessels suspected of being run by designated groups.

As operations intensify, U.S. forces are stepping up their efforts to dismantle narcotics trafficking networks by targeting routes frequently used for drug smuggling in the Pacific. This strategic focus aims to disrupt the activities of cartel operatives and curb the flow of illicit drugs.

Officials said intelligence confirmed those vessels were traveling along known drug trafficking routes in the Eastern Pacific and were actively engaged in narcotics operations.

Two men were killed in the first strike and three in the second, while one individual survived the initial attack.

SOUTHCOM said it immediately called on the U.S. Coast Guard to conduct search and rescue operations for the lone survivor. No U.S. forces were injured in either operation.

SOUTHCOM strikes drug-trafficking vessel in the Caribbean, killing 4 (U.S. Southern Command)

The operations are part of a broader U.S. military effort to disrupt cartel-linked trafficking networks at sea, with officials increasingly describing such groups using terrorism-related designations.

The strikes were carried out under Joint Task Force Southern Spear, an ongoing mission focused on targeting transnational criminal organizations operating along key maritime drug routes in the region.

The Eastern Pacific remains a major corridor for narcotics trafficking, where cartels frequently rely on small, fast-moving vessels to transport drugs north toward the U.S. and Central America.

Boat strike targeting alleged narco-terrorists (U.S. Southern Command)

The use of the term “Designated Terrorist Organizations” reflects a more aggressive posture by the Trump administration, which has expanded the use of military force against suspected narcotics traffickers beyond traditional law enforcement approaches.

SOUTHCOM has not released additional details about the identities of those killed or the specific groups involved.

The command is responsible for military operations in Central and South America and the Caribbean, including counter-narcotics missions aimed at disrupting drug trafficking networks that threaten U.S. interests.

The U.S. has carried out dozens of strikes on suspected drug-smuggling vessels in recent months as part of a broader campaign to dismantle cartel-linked trafficking operations and increase pressure on transnational criminal organizations.